DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10073 and CPQ

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_057218.1	Gene:	CPQ / 10404	HGNCID:	16910	Length:	472	Species:	Homo sapiens

Alignment Length:	257	Identity:	55/257 - (21%)
Similarity:	88/257 - (34%)	Gaps:	102/257 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 RIPTG-LTIEDASKGVFIAERAQSNLYKLAEIGTKVV-----GS----DNNENKTVDYLMG---- 118
            :|||. :|:|||..           :.::|..|.|:|     |:    |.:...||..:.|
Human   228 KIPTACITVEDAEM-----------MSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYP 281

  Fly   119 ----LVN------EIQENCLDDYFDIEVDLQEVSGSYIHWTMVNMYQGVQNIVIKLSPKNTT--- 170
                ||:      ::.:..:||          ..|::|.|..:::.:.     :.|.||.|.
Human   282 EQVVLVSGHLDSWDVGQGAMDD----------GGGAFISWEALSLIKD-----LGLRPKRTLRLV 331

  Fly   171 -----------STTYLLVNSHFDSKPTSPSAGDAGQMVVAILEVLRVMCSTK-QAIRHPVVFLLN 223
                       :..|..::....|..:.....|||..:...|:...   |.| :||...|:.||
Human   332 LWTAEEQGGVGAFQYYQLHKVNISNYSLVMESDAGTFLPTGLQFTG---SEKARAIMEEVMSLL- 392

  Fly   224 GAEENPLQ----ASHGFITQHKWAKNCKVVLNLDAAGNGGSDIVF--QTG-PNSPWLVEKYK 278
                .||.    .|||                      .|:||.|  |.| |.:..|.:.||
Human   393 ----QPLNITQVLSHG----------------------EGTDINFWIQAGVPGASLLDDLYK 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	48/244 (20%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401
CPQ	NP_057218.1	M28_Pgcp_like	47..449	CDD:193504	55/257 (21%)
CPQ	NP_057218.1	PA_M28_2	130..256	CDD:240119	11/38 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900