DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10073 and ermp1

DIOPT Version :9

Sequence 1:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	XP_005173917.3	Gene:	ermp1 / 101883637	-ID:	-	Length:	886	Species:	Danio rerio

Alignment Length:	890	Identity:	284/890 - (31%)
Similarity:	435/890 - (48%)	Gaps:	121/890 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 LATGFL-LFWALLFSAVVLPLFYRIPTGLTIEDASKGVFIAERAQSNLYKLAEIGTKVVGSDNNE 109
            |..||: |.|.|:..: |..|..|.|          |.|.|.||:.:|.::..:|.:.|||..||
Zfish    60 LLLGFVCLLWTLVHLS-VQQLIIRSP----------GTFNALRARKHLDQITSVGPRTVGSPENE 113

  Fly   110 NKTVDYLMGLVNEIQENCLDDYFDIEVDLQEVSGSY-IHWT--MVNMYQGVQNIVIKLSPKNTTS 171
            ..||:||:..:.:|:.........|.||:|:.:||: |.:.  ..:.|..|.||.:||.|| :::
Zfish   114 ILTVNYLLEQIEQIRSESRSGPHSITVDVQKPTGSFSIDFLGGFTSYYDRVTNIAVKLEPK-SSA 177

  Fly   172 TTYLLVNSHFDSKPTSPSAGDAGQMVVAILEVLRVMCSTKQAIRHPVVFLLNGAEENPLQASHGF 236
            ..::|.|.||||...||.|.|.......:||||..:.:....|:|.|:||.||||||.|||||||
Zfish   178 QHFMLANCHFDSVANSPGASDDAVSCSVMLEVLHSLANLSTPIKHGVIFLFNGAEENILQASHGF 242

  Fly   237 ITQHKWAKNCKVVLNLDAAGNGGSDIVFQTGPNSPWLVEKYKENAPHYLATTMAEEIFQTGILPS 301
            ||||.||:..:..:||:|||.||.::||||||.:||||:.|...|.|..|:.:.:|:||:||:||
Zfish   243 ITQHPWAQQVRAFINLEAAGVGGKEVVFQTGPENPWLVQAYVRAAVHPFASVVGQEVFQSGIIPS 307

  Fly   302 DTDFAIFVKYGNLIGLDMAKFINGFAYHTKYDQFSNIPRGSIQNTGDNLLGLVRSIANSTELDNT 366
            ||||.|:..:||:.|:|:|...|||.||||||....|...|||..|||:|.:::.:..|.||.::
Zfish   308 DTDFRIYRDFGNIPGIDLAFIENGFIYHTKYDTPERIHTDSIQRAGDNILSVLQHLVMSDELADS 372

  Fly   367 EAYATGHAIFFDVLGLYFISYTESNGVILNYSVAGVALVLIFLS--------IWRTSSISRVSIG 423
            ..|..|:.:|||||||..::|......|:||..|  |..|::||        :.....::.....
Zfish   373 SVYRHGNMVFFDVLGLMVVAYPARVAAIINYLTA--AATLVYLSRKCSGGAGVRYLRDVACAVCV 435

  Fly   424 HVLCWFILIFVLQIIAFVLGLGLPIVVAYVFDKYGLSI---TYFSTPVLLIGLYICPSLLGL-SL 484
            .||.||:.:..|.|:|.:|.|            .|.|:   |:|...|.|.|......::.: :|
Zfish   436 CVLSWFVTLLTLLIVALLLTL------------LGRSMFWYTHFYAAVCLYGSAAAAKIILIHTL 488

  Fly   485 PSYIYLKLQRSEKVGFAQHLQLVLHGHAAV-LAIL--DIG----------LTVYGLRSAYVPTWT 536
            ...:|..                  |.:|| ||.|  |:|          ||:.||.|||||...
Zfish   489 AKNLYYT------------------GVSAVDLAELFFDVGLLLWCCALVFLTLNGLCSAYVPMMM 535

  Fly   537 LIFYVIPLAVNLLTTLHDRGFSWTGVLKIFQV----VPFLYNSYLIYCFVVTLIPMMGRFGRATN 597
            ::|   ||...:|...|.|....:....:|.:    ||:::..:||:.......|::||.|....
Zfish   536 VVF---PLLSKVLLRTHFRAKGASLQYSVFYLMGLSVPYVHIMFLIWVVFEIFTPILGRSGTEIP 597

  Fly   598 PDLIISALCALGTILALGFVIPLVNMFRRPSLILLTLLAISAVTIYTASSTQIGFPY-------R 655
            ||::::||..|..::...:::.|:.:......:|..|.::.|| ::......:.|||       |
Zfish   598 PDVVLAALITLAAVILSSYLMHLLYLSCSTKRMLAALGSVFAV-MFVLVGCGLFFPYSADPSSPR 661

  Fly   656 PKTNVQRLPYLHVRRIFYEYDGTVVKNDSGYLFNFQDRRGPAPLK--LSKLNTTGLVSIAADCD- 717
            ||    |:...|..|:|:..||:|.::|||...|..|..|...:.  :.:||.    ||...|.
Zfish   662 PK----RVFVQHTTRVFHALDGSVERSDSGLWINSLDYTGMQHISAHVPQLND----SIRTRCQH 718

  Fly   718 TVMMCGFPLYDHRW---VKNRLQIMW-LPREEEIITPYEP-KLELLSKTELGNNTLRMNFQSATT 777
            |:..||||     |   ||..::..| ||  ...::|..| :..|||:.:....|||::|::...
Zfish   719 TLPYCGFP-----WFLPVKFLVKKSWYLP--APAVSPEAPLEFRLLSRQQSEWGTLRLSFEAKGP 776

  Fly   778 DHASVFIQPLEDVIISNWSLPTSYIGQQDTSHMYF---SYGKNNTALTFFIDFYKLDADFAVP-- 837
            .|.|:::.|:....:..||.... ..:.|.|..||   |:|.:..|..|.::.....:| |.|
Zfish   777 THMSLYLLPVSGASLIGWSFGDG-TPRFDLSGEYFIFYSHGTDAPAWRFSLEVQPGVSD-ASPDE 839

  Fly   838 -LCQIGLAVHFIG--NKGDAISQEFAKKIPSFAAAVDWPASYQRY 879
             |..:.::.|:..  :|............|.:|....|.::|..|
Zfish   840 GLLALAISAHYFSGPDKHSPPLHTLINTFPDWAFPSAWSSTYHMY 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	137/309 (44%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401	63/268 (24%)
ermp1	XP_005173917.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010