DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10062 and Tfr2

DIOPT Version :9

Sequence 1:	NP_001261089.1	Gene:	CG10062 / 37224	FlyBaseID:	FBgn0034439	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	XP_030110515.1	Gene:	Tfr2 / 50765	MGIID:	1354956	Length:	840	Species:	Mus musculus

Alignment Length:	229	Identity:	47/229 - (20%)
Similarity:	94/229 - (41%)	Gaps:	65/229 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ENYLLINSHYDSVPGSPGAGDDGSMVVTMLEVMRV---IAKSGDPLAHPIVFL-FNGAEENPLQA 210
            ::|::|.:..|:  ..|||.........:||::|.   :..:|......::|: ::|.:...:.|
Mouse   461 DHYVVIGAQRDA--WGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGA 523

  Fly   211 SHAFITQHKWAK------NCKAL--INLDSAGSGGREILFQSGPNH----PWLMNYYRNV----- 258
            :       :|.:      :.||:  ::||::..|       .|..|    |.|::...|:
Mouse   524 T-------EWLEGYLSVLHLKAVVYVSLDNSVLG-------DGKFHAKTSPLLVSLIENILKQVD 574

  Fly   259 -PHPFANTLAE-----------ELFQAGYIPSDTDFRIFRDYGGVPGLDMAYIFNGYVY---HTK 308
             |:....||.|           |:.|.  :|.|:....|..:.|||.::.:::.:..||   |||
Mouse   575 SPNHSGQTLYEQVALTHPSWDAEVIQP--LPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPFLHTK 637

  Fly   309 YN-----------RINAFPRASFQHTGDNVLSLA 331
            .:           |:.|..:|..|..|..::.|:
Mouse   638 EDTYENLHKMLRGRLPAVVQAVAQLAGQLLIRLS 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:193497	47/229 (21%)
Tfr2	XP_030110515.1	PA_TfR	248..438	CDD:239043
		M28_TfR	446..679	CDD:349946	47/229 (21%)
		TFR_dimer	706..830	CDD:367885
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900