DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10062 and naalad2

DIOPT Version :9

Sequence 1:	NP_001261089.1	Gene:	CG10062 / 37224	FlyBaseID:	FBgn0034439	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_956571.1	Gene:	naalad2 / 393247	ZFINID:	ZDB-GENE-040426-1025	Length:	745	Species:	Danio rerio

Alignment Length:	229	Identity:	46/229 - (20%)
Similarity:	80/229 - (34%)	Gaps:	57/229 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ENYLLINSHYDS-VPGSPGAGDDGSMVVTMLEVMRVIAKSGDPLAHPIVFLFNGAEENPLQASHA 213
            :.|:::..|.|: |.|........::|...:.....:.|.|......::|....|||..||.|
Zfish   356 DRYIILGGHRDAWVFGGIDPVSGAAVVHENVRAAGKLMKKGWRPRRTLIFASWDAEEFGLQGS-- 418

  Fly   214 FITQHKWAK-NCKAL-------INLDSAGSGGREILFQSGPN-HPWLMNYYRNVPHPFANTLAEE 269
                .:||: |.:.|       ||.|||..|...:.....|: |..:.:..:.|..|........
Zfish   419 ----TEWAEDNARVLQERAVAYINADSAIEGMYTLRVDCTPSLHTLVYDITKKVLSPEEGEEGMS 479

  Fly   270 LFQAGY---------------IPSDTDFRIFRDYGGVPGLDMAYI-------FNGY-VYHT---- 307
            |:::.:               :.|.:||..:....|:......|.       ::.| |||:
Zfish   480 LYESWHKRDNWPEKDKPWISKLGSGSDFEAYFIRLGITSGRARYTKNRKTERYSSYPVYHSVYET 544

  Fly   308 ----------KYNRINAFPRASFQHTGDNVLSLA 331
                      ::.|:.|..|.    .|..:.|||
Zfish   545 YEIVERFYDPRFRRLEAVARV----RGGLIFSLA 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:193497	46/229 (20%)
naalad2	NP_956571.1	Zinc_peptidase_like	47..>102	CDD:301362
		PA_GCPII_like	108..333	CDD:239036
		M28_PSMA_like	341..581	CDD:193568	46/229 (20%)
		TFR_dimer	618..733	CDD:282153
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900