DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10062 and Naaladl1

DIOPT Version :9

Sequence 1:	NP_001261089.1	Gene:	CG10062 / 37224	FlyBaseID:	FBgn0034439	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_001009546.1	Gene:	Naaladl1 / 381204	MGIID:	2685810	Length:	745	Species:	Mus musculus

Alignment Length:	223	Identity:	54/223 - (24%)
Similarity:	82/223 - (36%)	Gaps:	66/223 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 KLSEKNSTN-----------ENYLLINSHYDSVPGSPGAGDDGSMVVTMLEVMRVIA---KSGD- 190
            :|..:.|:|           :.|::..:|.||  ...||.|..|....:||:.||:.   |.|.
Mouse   345 RLELRTSSNVLGIIQGAVEPDRYVIYGNHRDS--WVHGAVDPSSGTAVLLEISRVLGTLLKKGTW 407

  Fly   191 -PLAHPIVFLFNGAEENPLQASHAFITQ--HKWAKNCKALINLD-SAGSGG----------REIL 241
             | ...|:|...||||..|..|..|..:  .|..:...|.||:| |..|..          :.::
Mouse   408 RP-RRSIIFASWGAEEFGLIGSTEFTEEFLSKLQERTVAYINVDISVFSNATLRAQGTPPVQSVI 471

  Fly   242 FQ-----SGPNHPWLMNY-----YRNVPHPFANTLAEELFQAGYIPS------DTDFRIFRDYGG 290
            |.     |.|....|..|     |.|...|.          .|.:||      .:|:..|..:.|
Mouse   472 FSATKEISAPGSSGLSIYDNWIRYTNRTSPV----------YGLVPSLGTLGAGSDYAAFVHFLG 526

  Fly   291 VPGLDMAYIFNGY--------VYHTKYN 310
            :..:|:||.::..        .|||.::
Mouse   527 ITSMDLAYTYDRSKTSARIYPTYHTAFD 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:193497	54/223 (24%)
Naaladl1	NP_001009546.1	Zinc_peptidase_like	53..>126	CDD:387401
		PA_GCPII_like	114..344	CDD:239036
		M28_PSMA_like	<350..592	CDD:349942	53/218 (24%)
		TFR_dimer	<642..739	CDD:367885
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900