DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10062 and CG9416

DIOPT Version :9

Sequence 1:	NP_001261089.1	Gene:	CG10062 / 37224	FlyBaseID:	FBgn0034439	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster

Alignment Length:	869	Identity:	408/869 - (46%)
Similarity:	569/869 - (65%)	Gaps:	45/869 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KLQWYYAPAFFGFWLVLYLSLVNTQMNHMPRPLTRSDEASHPNSFIAQRAEDTLIELTRIGPRVV 82
            |:.||:||.|...|.:|:..:|....:.||:..|..||...|..||.:|||:||:.|::|||:||
  Fly    16 KIGWYWAPLFVSCWFLLFYLVVIPSFHRMPQLKTLEDERQQPGQFIGERAENTLLRLSKIGPKVV 80

  Fly    83 GSMANEESAVEFLRAEVAK-VESEMSDLLEIEVDVQQASGAYMHWEMVNMYQGIQNVVVKLSEKN 146
            ||.|||:.||:||.:|:.. ::...:||.:||.|||.|||.|:.|.|||:||.|||||||||.||
  Fly    81 GSAANEQVAVQFLLSEIGDIIDDARTDLYDIEKDVQVASGNYLLWSMVNVYQSIQNVVVKLSPKN 145

  Fly   147 STNENYLLINSHYDSVPGSPGAGDDGSMVVTMLEVMRVIAKSGDPLAHPIVFLFNGAEENPLQAS 211
            :|:|..||||||:||||||.||||.|.|.|.||||:|||.|...||.:.:|||||||||||||.|
  Fly   146 ATSEAALLINSHFDSVPGSSGAGDAGMMCVIMLEVLRVITKYETPLTYSVVFLFNGAEENPLQGS 210

  Fly   212 HAFITQHKWAKNCKALINLDSAGSGGREILFQSGPNHPWLMNYY-RNVPHPFANTLAEELFQAGY 275
            |||||||.||:|.:|:|||||||||||||||||||:|||||.|| :|:.||||:|:.|||||.|:
  Fly   211 HAFITQHPWAQNIRAVINLDSAGSGGREILFQSGPDHPWLMKYYGKNIVHPFASTIGEELFQNGF 275

  Fly   276 IPSDTDFRIFRDYGGVPGLDMAYIFNGYVYHTKYNRINAFPRASFQHTGDNVLSLARALANAPEL 340
            :||:||:|:|||||.:||||||...|||||||||:|.|..||.::|.||:|:|:|.:|||||.||
  Fly   276 VPSETDYRVFRDYGHIPGLDMAQTLNGYVYHTKYDRFNLIPRRTYQLTGENILALVKALANAEEL 340

  Fly   341 DDTAAHSEGHNIFYDFLGWFMIFYTETTSIIVNVVVTLLALLGVGISIYFMSLRSGCSWKGVLLR 405
            ::.:.::|||.||:|.:|||.::|.|||.||:|:.|.:|..:.:.:.|:.||..:|...:.:..:
  Fly   341 ENPSKYAEGHMIFFDMMGWFFVYYPETTGIIINITVCVLVCVTIVLYIWMMSSSTGMFRRRIWAK 405

  Fly   406 FSISIAIQFVSLILAIGLALLVALFMDGVDRSMSWFTSSWTIFGLYLAPIVFGLSILPALYLEKT 470
            |.|..|:|...:.|.|||.:.:|||:|.|:..||||:.:|.:||||..|::||:.|:||:|..:|
  Fly   406 FGILAALQLAGVALGIGLVISIALFLDAVNLPMSWFSQNWMLFGLYFCPMIFGMGIVPAIYFSRT 470

  Fly   471 KRDPLGLGFRIQLFMHSHCICLIVIMLTLTGLSIRSAYLIMLCILFDIVALIVNLVTKWHRKAYL 535
            |...|.||:.|||.|||||:.|.:|...:...|||||::|||||.|..:::::|||||.|:..:|
  Fly   471 KEHGLPLGYGIQLLMHSHCLILTIITAIMVSYSIRSAFVIMLCIGFYTLSVLINLVTKAHKTNFL 535

  Fly   536 FAIAVTVCQILPLVFFTYLCTVALVTLMPMQGRSGSSTNPDMVIAALVWLFSLMFAGFIAPLIMF 600
            :.|...:||:||.:|:||.|....|..:|||||. .:|||::::.....|..|:||.|:.||...
  Fly   536 WLIPHCICQVLPFMFYTYCCYAFYVVFVPMQGRE-CNTNPEILMGFFTALMVLLFAPFLVPLFCL 599

  Fly   601 FRKTRTIVLCFLGITILFIIIAVTNAGFPYKEKTSPQRYSLIHAHRRLHNADGSTRID--ESGLY 663
            |||::||:..|...||:|||.|.|...|||.|||:|||:..:|..|..||.|.::.:.  :||.:
  Fly   600 FRKSKTIISMFGICTIVFIIFAATPIAFPYAEKTAPQRFFAVHTARTFHNGDPASTVSHKDSGYF 664

  Fly   664 IYPQDRRFGIAKDNIAAIGEAHQVSDF--------------CDEEMFCGMPLYNHRWNKARQYSM 714
            :.|.|||             .|.|.|.              ||.|:.||.|:|:.||..|...|.
  Fly   665 VLPVDRR-------------PHTVDDILFENTNFTKSERIDCDSELMCGFPIYSSRWLNAVDNSY 716

  Fly   715 WIETSESPEIPTEY-PML-VLQDSSELETSAQRRFNFTLAGPSHMGIFINVKNDARILNWSFNDT 777
            ::   ..||...|| |.| :|:.||..:|:.  ||:..::||.|..|||...||:::::|||...
  Fly   717 FV---PGPEPNREYIPTLTILEKSSNSDTNI--RFDLEISGPDHTSIFILPLNDSKLVDWSFIRD 776

  Fly   778 LIREQAEPPYMVYFSYGLDDSPLEFTIDVELNDYLQKTTSTFDTPTLEIGIGGHWVTQDITAIEK 842
            .:....:|||.||:||.||..||:|:::.|..|      ..:...|.:|.:.||.:..|:...|.
  Fly   777 PLDGNVKPPYYVYWSYALDPKPLQFSLEFEHED------PNWSGGTFKIALMGHRIHDDMYITED 835

  Fly   843 LSSYINRFPSYAYIQGWVGTYETW 866
            ...::..||.:|::..|:|:|.:|
  Fly   836 FREFLATFPPWAHVSSWLGSYNSW 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:193497	197/306 (64%)
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	197/306 (64%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372	92/201 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446913
Domainoid	1	1.000	161	1.000	Domainoid score	I1255
eggNOG	1	0.900	-	-		E1_COG2234
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	212	1.000	Inparanoid score	I1244
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D14040at33392
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm25001
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	P	PTHR12147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X435
	12	11.800