DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10062 and gcp-2.2

DIOPT Version :9

Sequence 1:	NP_001261089.1	Gene:	CG10062 / 37224	FlyBaseID:	FBgn0034439	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_509928.3	Gene:	gcp-2.2 / 183230	WormBaseID:	WBGene00007954	Length:	779	Species:	Caenorhabditis elegans

Alignment Length:	225	Identity:	61/225 - (27%)
Similarity:	100/225 - (44%)	Gaps:	52/225 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 MHWEMVNMYQGIQNVV--VKLSEKNSTNENYLLINSHYDSVPGSPGAGDDGSMVVTMLEVMRVIA 186
            :|.|  |..:.|||::  :|.|::   .:.::|:::|||:  .:.||.|..|...|:|||.|.:.
Worm   364 VHAE--NEERKIQNIMGYIKGSQE---PDKFVLVSNHYDA--WTYGAVDPNSGTSTLLEVSRALK 421

  Fly   187 ----KSGDPLAHPIVFLFNGAEENPLQASHAFITQHK--WAKNCKALINLDSAGSGGREILFQSG 245
                ::|...|..|:|....|||..|..|..|..:::  ..:...|:||:|..| |.:.:|   |
Worm   422 QYQNQTGWIPARSILFAHWDAEEYGLIGSTEFAEEYRLQLMRRAVAVINMDLIG-GNQTLL---G 482

  Fly   246 PNHPWLMNYYR----NVPHPFANTLAE---ELFQAG--YIPS---------------DTDFRIFR 286
            .::|.:.|..|    ||..|....:.:   .|:.:.  |.||               .:|...|.
Worm   483 LSNPTVANVLRSAAANVEQPNPTEMEQGRKTLYDSWKYYAPSKNNRSTHPYQRIPAGGSDHLPFF 547

  Fly   287 DYGGVP-------GLDMAYIFNGYVYHTKY 309
            ||.|:|       .||....:.  :|||.|
Worm   548 DYLGIPIVFFITSSLDAPPTYP--LYHTIY 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:193497	61/225 (27%)
gcp-2.2	NP_509928.3	Zinc_peptidase_like	75..>133	CDD:301362
		PA_GCPII_like	137..364	CDD:239036	61/225 (27%)
		M28_PSMA_like	372..614	CDD:193568	58/215 (27%)
		TFR_dimer	652..773	CDD:282153
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900