Protein Alignment CG10062 and B0495.7

DIOPT Version :10

• Sequence 1: NP_001261089.1
• Gene: CG10062 / 37224
• FlyBaseID: FBgn0034439
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_495618.1
• Gene: B0495.7 / 174245
• WormBaseID: WBGene00015206
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 891
• Identity: 260/891 - (29%)
• Similarity: 424/891 - (47%)
• Gaps: 110/891 - (12%)

  Fly    28 FGFWL--VLYLSLVNTQMNHMPRPLTRSDEASHPNSFIAQRAEDTLIELTRIGPRVVGSMANEES 90
            |..|:  ||.:::|...:..:.|.:....:.:....|..|||...|.:||.:|.|..||...|..
 Worm    37 FRHWIYFVLTVAIVYAGVVALHRKMPAVRDGTSFEDFSEQRARVLLKQLTALGSRPSGSDNLEVK 101

  Fly    91 AVEFLRAEVAKVESEMSD--LLEIEVDVQQASGAY---MHWEMVNMYQGIQNVVVKLSEKNSTNE 150
            |...::..:.|:.|.:.:  :..:|.|||:.||.:   ........|..|.||||::..|...:.
 Worm   102 AFGMIQDRIGKIHSVVDEVGVNRLESDVQRPSGCFDLKFLSSFTLCYHKITNVVVRIGPKKGPSG 166

  Fly   151 NYLLINSHYDSVPGSPGAGDDGSMVVTMLEVMRVIAKSGDPLAHPIVFLFNGAEENPLQASHAFI 215
            |.||:|.|:|::|.:|||.||......|::|:.|:|.|...|.:.:||||||||||.|||:|.||
 Worm   167 NSLLLNCHFDTMPDTPGATDDAVACTIMMDVLEVLAHSKTELENDVVFLFNGAEENFLQAAHGFI 231

  Fly   216 TQHKWAKNCKALINLDSAGSGGREILFQSGPNHPWLM-NYYRNVPHPFANTLAEELFQAGYIPSD 279
            .||.|..:.:|.|||:..||||||||||:||.:.||: .|..|.||||.:.||:|:||:|.||||
 Worm   232 NQHPWRHDIRAFINLEGTGSGGREILFQAGPGNSWLLQTYLENAPHPFCSVLAQEIFQSGIIPSD 296

  Fly   280 TDFRIFRDYGGVPGLDMAYIFNGYVYHTKYNRINAFPRASFQHTGDNVLSLARALANAPELDDTA 344
            ||||||||||.:.|||:||..||:.|||:::........:.|..|:|||::.||:..:|.|:..|
 Worm   297 TDFRIFRDYGRISGLDIAYTKNGWFYHTEFDEEWRIEPGAIQRAGENVLAVVRAILKSPYLEKPA 361

  Fly   345 AHSEGHN-IFYDFLGWFMIFYTETTSIIVNVVVTLLALLGVGISIYFMSLRSGCSWKGVLLR--- 405
            ...|.:. :|||.:|.|.::|:.....::|.:..        .:.||:          |:||
 Worm   362 TFDEENRWVFYDVVGLFTVYYSVNVGKLLNYIAC--------FATYFL----------VVLRIRN 408

  Fly   406 --FSI-SIAIQF----VSLILAIGLALLVALFMDGVDRSMSWFTSSWTIFGLYLAPIVFGLSILP 463
              :|: .:||.|    |:.:..:...||:..|:..:|..|.|:.....:..||:.|::...:|:.
 Worm   409 RLYSVGDLAIAFKHHVVAFLAMVITMLLIIAFVVQMDLVMCWYKMPEIVGALYVLPMLIAGAIVH 473

  Fly   464 ALY--------LEKTKRDPLGLGFRIQLFMHSHCICLIVIMLTLTGLSIRSAYLIM----LCILF 516
            :.|        :|..:.|.:.|.|...||:             :|..::.||:.::    |.:..
 Worm   474 SHYADNNRIRNVEMVQYDTILLSFASILFL-------------MTFYNLSSAFYVLNNLILPVFK 525

  Fly   517 DIVALIVNL--VTKWHRKAYLFAIAVTVCQILPLVFFTYLCTVALVTLMPMQGRSGSSTNPDMVI 579
            ||:...:.|  |.:......|| .....|.:...||..|..:..:...:|:.||.|::.||:.::
 Worm   526 DIIIWALGLFGVIRRVTPRVLF-FTQLFCFLPTFVFAAYAISQCVDFFVPVMGRLGNAINPEFIM 589

  Fly   580 AALVWLFSLMFAGFIAPLIMFFRKTRTIVLCFLGITILFIIIAV-TNAGFPYK---EKTSPQRYS 640
            ..|..:.:..|..|:..|....|:...|:.....|..|||::.: |..|.||:   |....:|..
 Worm   590 GPLGLVIASGFILFVNNLFYISRRMNYIIRLLFAIFALFILVLITTKVGNPYEYSHENPRLRRII 654

  Fly   641 LIHAHRRLHNADGSTRIDESGLYIYPQDRR--FGIAKDNIAAIGEAHQVSDFCDEEMFCGMPLYN 703
            .:||:|.:::.:|.....::.|:::..|.|  ..:...:......|...:...||  :|.||.|.
 Worm   655 ALHANRTIYDFEGHLTQKDNALFVHSLDYRGASDLPDHSFLQGSSAPNCTGVVDE--YCRMPYYT 717

  Fly   704 --HRWNKARQYSMWIETSESPEIPTEYPMLVLQDSSELETSAQ-RRFNFTL---AGPSHMGIFIN 762
              |......| |:|:.......:|  ||:    |...:...|. ...|.|.   .|...|.:.:.
 Worm   718 AIHELFPPEQ-SLWVPVPSPVVLP--YPI----DLKLVSRHAMGENLNLTFEIRGGYDKMSLHVT 775

  Fly   763 VKNDARILNWSFNDTLIRE-QAEPPYMVYFSYGLDDSPLEFTIDVELNDY---LQKTTSTFDTP- 822
            ..||..:|:|||.|..|:| .....|.|:.:|| .::|       |:..:   |:........|
 Worm   776 PLNDYDLLSWSFTDIDIKEFGRRQTYFVFMTYG-HEAP-------EVRRFWILLKNKNGVAPDPE 832

  Fly   823 ---TLEIGIGGHW---VTQDITAIEKLSSYIN---RFPSYAYIQGW 859
               .:|:.:..|:   :.||...:.:|.:.|:   :.|..|.  ||
 Worm   833 KHENIELSVATHYAHGIYQDTETLRQLRAMISSRRQTPEQAV--GW 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:349872	135/311 (43%)
B0495.7	NP_495618.1	M28_Fxna_like	71..382	CDD:349872	135/310 (44%)