DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10062 and ermp1

DIOPT Version :9

Sequence 1:	NP_001261089.1	Gene:	CG10062 / 37224	FlyBaseID:	FBgn0034439	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	XP_005173917.3	Gene:	ermp1 / 101883637	-ID:	-	Length:	886	Species:	Danio rerio

Alignment Length:	879	Identity:	282/879 - (32%)
Similarity:	450/879 - (51%)	Gaps:	94/879 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GF----WLVLYLSLVNTQMNHMPRPLTRSDEASHPNSFIAQRAEDTLIELTRIGPRVVGSMANEE 89
            ||    |.:::||        :.:.:.||     |.:|.|.||...|.::|.:|||.|||..||.
Zfish    63 GFVCLLWTLVHLS--------VQQLIIRS-----PGTFNALRARKHLDQITSVGPRTVGSPENEI 114

  Fly    90 SAVEFLRAEVAKVESE-MSDLLEIEVDVQQASGAY---MHWEMVNMYQGIQNVVVKLSEKNSTNE 150
            ..|.:|..::.::.|| .|....|.||||:.:|::   ......:.|..:.|:.|||..|:|. :
Zfish   115 LTVNYLLEQIEQIRSESRSGPHSITVDVQKPTGSFSIDFLGGFTSYYDRVTNIAVKLEPKSSA-Q 178

  Fly   151 NYLLINSHYDSVPGSPGAGDDGSMVVTMLEVMRVIAKSGDPLAHPIVFLFNGAEENPLQASHAFI 215
            :::|.|.|:|||..||||.||......||||:..:|....|:.|.::|||||||||.|||||.||
Zfish   179 HFMLANCHFDSVANSPGASDDAVSCSVMLEVLHSLANLSTPIKHGVIFLFNGAEENILQASHGFI 243

  Fly   216 TQHKWAKNCKALINLDSAGSGGREILFQSGPNHPWLMN-YYRNVPHPFANTLAEELFQAGYIPSD 279
            |||.||:..:|.|||::||.||:|::||:||.:|||:. |.|...||||:.:.:|:||:|.||||
Zfish   244 TQHPWAQQVRAFINLEAAGVGGKEVVFQTGPENPWLVQAYVRAAVHPFASVVGQEVFQSGIIPSD 308

  Fly   280 TDFRIFRDYGGVPGLDMAYIFNGYVYHTKYNRINAFPRASFQHTGDNVLSLARALANAPELDDTA 344
            |||||:||:|.:||:|:|:|.||::|||||:........|.|..|||:||:.:.|..:.||.|::
Zfish   309 TDFRIYRDFGNIPGIDLAFIENGFIYHTKYDTPERIHTDSIQRAGDNILSVLQHLVMSDELADSS 373

  Fly   345 AHSEGHNIFYDFLGWFMIFYTETTSIIVNVVVTLLALLGVGISIYFMSLRSGCSWKGVLLRFSIS 409
            .:..|:.:|:|.||..::.|....:.|:|.:.....|      :|.....||.:....|...:.:
Zfish   374 VYRHGNMVFFDVLGLMVVAYPARVAAIINYLTAAATL------VYLSRKCSGGAGVRYLRDVACA 432

  Fly   410 IAIQFVSLILAIGLALLVALFMDGVDRSMSWFTSSWTIFGLY----LAPIVFGLSILPALYLEKT 470
            :.:..:|..:.:...|:|||.:..:.|||.|:|..:....||    .|.|:...::...||....
Zfish   433 VCVCVLSWFVTLLTLLIVALLLTLLGRSMFWYTHFYAAVCLYGSAAAAKIILIHTLAKNLYYTGV 497

  Fly   471 KR-DPLGLGFRIQLFMHSHCICLIVIMLTLTGLSIRSAYLIMLCILFDIVALIVNLVTKWHRKA- 533
            .. |...|.|.:.|.:.    |..::.|||.||.  |||:.|:.::|.:::.:: |.|.:..|.
Zfish   498 SAVDLAELFFDVGLLLW----CCALVFLTLNGLC--SAYVPMMMVVFPLLSKVL-LRTHFRAKGA 555

  Fly   534 -------YLFAIAVTVCQILPLVFFTYLCTVALVTLMPMQGRSGSSTNPDMVIAALVWLFSLMFA 591
                   ||..::|      |.|...:|..|......|:.||||:...||:|:|||:.|.:::.:
Zfish   556 SLQYSVFYLMGLSV------PYVHIMFLIWVVFEIFTPILGRSGTEIPPDVVLAALITLAAVILS 614

  Fly   592 GFIAPLIMFFRKTRTIVLCFLG--ITILFIIIAVTNAGFPYKEKTS---PQRYSLIHAHRRLHNA 651
            .::..|:.....|:. :|..||  ..::|:::. ....|||....|   |:|..:.|..|..|..
Zfish   615 SYLMHLLYLSCSTKR-MLAALGSVFAVMFVLVG-CGLFFPYSADPSSPRPKRVFVQHTTRVFHAL 677

  Fly   652 DGSTRIDESGLYIYPQDRRFGIAKDNIAAIGEAHQVSDF----CDEEM-FCGMPLYNHRWNKARQ 711
            |||....:|||:|...|.   ....:|:|  ...|::|.    |...: :||.|     |....:
Zfish   678 DGSVERSDSGLWINSLDY---TGMQHISA--HVPQLNDSIRTRCQHTLPYCGFP-----WFLPVK 732

  Fly   712 Y---SMWI--ETSESPEIPTEYPMLVLQDSSELETSAQRRFNFTLAGPSHMGIFINVKNDARILN 771
            :   ..|.  ..:.|||.|.|:.:|..| .||..|   .|.:|...||:||.:::...:.|.::.
Zfish   733 FLVKKSWYLPAPAVSPEAPLEFRLLSRQ-QSEWGT---LRLSFEAKGPTHMSLYLLPVSGASLIG 793

  Fly   772 WSFNDTLIREQAEPPYMVYFSYGLDDSPLEFTIDVE--LNDYLQKTTSTFDTPTLEIGIGGHWVT 834
            |||.|...|......|.:::|:|.|.....|:::|:  ::|      ::.|...|.:.|..|:.:
Zfish   794 WSFGDGTPRFDLSGEYFIFYSHGTDAPAWRFSLEVQPGVSD------ASPDEGLLALAISAHYFS 852

  Fly   835 QDITAIEKLSSYINRFPSYAYIQGWVGTYETWYF 868
            ........|.:.||.||.:|:...|..||..:.:
Zfish   853 GPDKHSPPLHTLINTFPDWAFPSAWSSTYHMYRY 886

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:193497	139/309 (45%)
ermp1	XP_005173917.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010