DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9416 and TRE2

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_014899.1	Gene:	TRE2 / 854430	SGDID:	S000005782	Length:	809	Species:	Saccharomyces cerevisiae

Alignment Length:	236	Identity:	52/236 - (22%)
Similarity:	87/236 - (36%)	Gaps:	67/236 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 LSEIGDIIDDARTD----------LYDIEKDVQVASGNYLLWSMVNVYQSIQNVVVKLSPKNATS 148
            ||..|..:||..:|          |.|::....|...::           |.|:|.|:..:..:.
Yeast   384 LSSGGVTVDDGNSDRSNSGKMGDVLIDVDLQTNVREKHF-----------IPNIVGKIEGREQSD 437

  Fly   149 EAALLINSHFDSVPGSS--GAGDAGMMCVIML--EVLRVITKYE---TPLTYSVVFLFNGAEENP 206
            :|.::..|......|::  ..|.|.::.::.|  ||     ||:   .||.......|.|.|.|
Yeast   438 KAIIIAASRNSINFGTTYPNFGTAALLSIVQLFQEV-----KYKFGWKPLRNIYFISFGGTEFN- 496

  Fly   207 LQGSHAFITQH--PWAQNIRAVINLDSAGSGGREILFQSG--------PDHPWLMKYYGK----- 256
            ..||...:.|.  |....|.::|::...|....| .:::|        ..||.|.|::.:
Yeast   497 YAGSSELVEQRLTPLKDEIYSLIDISQLGIPFAE-KYENGKTRGELSIETHPLLKKFFNRNAHGN 560

  Fly   257 ------NIVH-----PF------ASTIGEELFQNGFVPSET 280
                  |:.|     ||      .|.|..:..:|...|:||
Yeast   561 FDISVDNVQHYGDWTPFLANGIPVSVISSDSTRNRDTPTET 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	52/236 (22%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
TRE2	NP_014899.1	PA	249..392	CDD:238300	3/7 (43%)
		M28_PMSA_TfR_like	417..643	CDD:349871	44/203 (22%)
		TFR_dimer	668..799	CDD:398094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900