DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9416 and VPS70

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_012660.1	Gene:	VPS70 / 853590	SGDID:	S000003887	Length:	811	Species:	Saccharomyces cerevisiae

Alignment Length:	263	Identity:	60/263 - (22%)
Similarity:	105/263 - (39%)	Gaps:	58/263 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 VKLSPKNATSEAALLINSHFDSVPGSSGAGDAGMMCVIMLEVLRVITKY----ETPLTYSVVFLF 199
            |::|.....:|..::|.:|.||: .||.||||.....|:||:.|.::|.    ..||....:..:
Yeast   427 VEVSIPGIFTEGEIIIGAHRDSL-ASSSAGDANSGSAILLEIARGMSKLLKHGWKPLRPIKLISW 490

  Fly   200 NGAEENPLQGSHAFITQHPWAQNIRAVI--NLDSAGSGG----------REILFQSGP------- 245
            :| |.:.|.||..:...|......||::  |||:|.||.          :::::::..
Yeast   491 DG-ERSGLLGSTDYAEAHAAILRRRALVYLNLDNAISGTNFHCKANPLLQDVIYEAAKLTEFNGH 554

  Fly   246 ------DHPWLMKYYGKNIVHPFASTIGEELFQNGFVPSETDYRVFRDYGHIPGLDM---AQTLN 301
                  || |  ||...       :||       ..:...:.|..|:.:..:|....   |...:
Yeast   555 EDWSLFDH-W--KYTSN-------ATI-------SLLDGLSSYTSFQYHLGVPAAHFQFNANDTS 602

  Fly   302 GYVYHTK--YDRFNLIPRRT---YQLTGENILALVKALANAEELENPSKYAEGHMIFFDMMGWFF 361
            |.|||:.  :|....:.:.|   |:|  .|.:|:...|......||.......|:....:..|:.
Yeast   603 GAVYHSNSVFDSPTWLEKFTNSDYKL--HNTMAMFVGLTTLMLSENELARFNTHVYLKKIYNWYI 665

  Fly   362 VYY 364
            .::
Yeast   666 AWH 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	60/261 (23%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
VPS70	NP_012660.1	Zinc_peptidase_like	135..>187	CDD:417508
		PA_GCPII_like	187..413	CDD:239036
		M28_PMSA_TfR_like	419..649	CDD:349871	58/242 (24%)
		TFR_dimer	<731..799	CDD:398094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900