DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9416 and Naaladl1

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_113947.1	Gene:	Naaladl1 / 83568	RGDID:	620987	Length:	745	Species:	Rattus norvegicus

Alignment Length:	349	Identity:	81/349 - (23%)
Similarity:	127/349 - (36%)	Gaps:	93/349 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PGQFIG-ERAENTLLRLS----------------KIGPKVVGSAANEQVAVQFLLSEIGDIIDDA 104
            |.|.|| |.|:|.|..|:                |:||   |...|..
  Rat   287 PTQPIGFEDAKNLLCNLNGTSAPDSWQGALGCEYKLGP---GFEPNGN----------------- 331

  Fly   105 RTDLYDIEKDVQVASGNYL-LWSMVNVYQSIQNVVVKLSPKNATSEAALLINSHFDSVPGSSGAG 168
                :....:|:|:..|.| |.:..||...||..|        ..:..::..:|.||  ...||.
  Rat   332 ----FPAGSEVKVSVYNRLELRNSSNVLGIIQGAV--------EPDRYVIYGNHRDS--WVHGAV 382

  Fly   169 DAGMMCVIMLEVLRVITKYETPLTY----SVVFLFNGAEENPLQGSHAFITQHPWAQNIRAV--I 227
            |......::||:.||:.......|:    |::|...||||..|.||..|..:.......|.|  |
  Rat   383 DPSSGTAVLLEISRVLGTLLKKGTWRPRRSIIFASWGAEEFGLIGSTEFTEEFLSKLQERTVTYI 447

  Fly   228 NLDSAGSGGREILFQSGPDHPWLMKYYGKNIVHPFASTIGEELFQN------------GFVPS-- 278
            |:|.:......:..|..|....::....|.|..|.:|  |..::.|            |.|||
  Rat   448 NVDISVFSNATLRAQGTPPVQSVIFSATKEISAPGSS--GLSIYDNWIRYTNRSSPVYGLVPSMG 510

  Fly   279 ----ETDYRVFRDYGHIPGLDMAQTLNGY--------VYHTKYDRFNLIPR------RTYQLTGE 325
                .:||..|..:..|..:|:|.|.:..        .|||.:|.|:.:.:      .::|....
  Rat   511 TLGAGSDYASFIHFLGITSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVAR 575

  Fly   326 NILALVKALANAEELE-NPSKYAE 348
            ...:::..|:::..|. |.|.|:|
  Rat   576 TAGSVLLRLSDSLFLPLNVSDYSE 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	81/349 (23%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
Naaladl1	NP_113947.1	Zinc_peptidase_like	53..>126	CDD:387401
		PA_GCPII_like	119..331	CDD:239036	14/46 (30%)
		M28_PSMA_like	<353..592	CDD:349942	58/250 (23%)
		TFR_dimer	621..740	CDD:367885
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900