DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9416 and Naalad2

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_001344328.1	Gene:	Naalad2 / 72560	MGIID:	1919810	Length:	778	Species:	Mus musculus

Alignment Length:	465	Identity:	92/465 - (19%)
Similarity:	151/465 - (32%)	Gaps:	132/465 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IGWYWAPLFVSCWFLLFYLVVIPSFHRMPQLKTLEDERQQPGQFIGERAENTLLRLSKIGPKVVG 81
            :||:..||..:        .....:|:..|.|.|.:.:       .|...:.|...:|: |.:.|
Mouse    65 VGWFIKPLKET--------TTSAGYHQSIQQKLLSEMK-------AENIRSFLRSFTKL-PHLAG 113

  Fly    82 SAANEQVA--VQFLLSEIGDIIDDARTDLYDI-----------------EKDVQVASGNYLLWSM 127
            :..|..:|  :|....:.|  :|.|....||:                 |..|::...:| |...
Mouse   114 TEQNLLLAKKIQTQWKKFG--LDSANLVHYDVLLSYPNETNANYVSIVDEHGVEIFKTSY-LEPP 175

  Fly   128 VNVYQSIQNVVVKLSPKNATS-----EAALLINSHFDSVPGSSGAGDAGMMCVIMLEVLRVITKY 187
            .:.|:::.|::   .|.||.|     |..|:..::..:........:..:.|...:.:.|
Mouse   176 PDGYENVTNII---PPYNAFSASGMPEGELVYVNYARTEDFFKLEREMNINCTGKIVIAR----- 232

  Fly   188 ETPLTYSVVFLFNGAEENPLQGSHAFITQH-------PWAQNIRAVINLDSAGSGGREILFQSGP 245
                 |..:|..|..:...|.|:...|...       |..|......||..|.:....:|..:|.
Mouse   233 -----YGKIFRGNKVKNAMLAGAMGIILYSDPADYFAPDVQPYPKGWNLPGAAAQRGNVLNLNGA 292

  Fly   246 DHPWLMKYYGK---------------NI-VHPFASTIGEELFQN--GFVPSETDYR--VFRDYGH 290
            ..|....|..|               || |||......|.|.:|  |..|.:..::  :...|..
Mouse   293 GDPLTPGYPAKEYTFRLPVEEAVGIPNIPVHPIGYNDAERLLRNLGGAAPPDKSWKGSLNVSYNI 357

  Fly   291 IPGLDMAQTLNGYVYHTKYDRFNLIPRRTYQLTGENILALVKALANAEELENPSKYA--EGHMIF 353
            .||...::.......|.  :..|.| .|.|     |::..::...      .|.:|.  .||
Mouse   358 GPGFTGSEYSRNIRMHV--NNINKI-TRIY-----NVIGTIRGST------EPDRYVILGGH--- 405

  Fly   354 FDMMGWFFVYYPETTGIIINITVCVLVCVTIVLYIWMMSSSTGMF-------RRRI----W--AK 405
              ...|.|.....|||             |.||.  .::.|.|..       ||.|    |  .:
Mouse   406 --RDSWVFGGIDPTTG-------------TAVLQ--EIARSFGKLVNGGWRPRRTIIFASWDAEE 453

  Fly   406 FGILAALQLA 415
            ||:|.:.:.|
Mouse   454 FGLLGSTEWA 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	68/359 (19%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
Naalad2	NP_001344328.1	Zinc_peptidase_like	86..>142	CDD:326366	14/65 (22%)
		PA_GCPII_like	148..374	CDD:239036	43/239 (18%)
		M28_PSMA_like	376..623	CDD:193568	27/120 (23%)
		TFR_dimer	660..771	CDD:309400
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900