DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9416 and Tfr2

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	XP_030110515.1	Gene:	Tfr2 / 50765	MGIID:	1354956	Length:	840	Species:	Mus musculus

Alignment Length:	351	Identity:	71/351 - (20%)
Similarity:	119/351 - (33%)	Gaps:	88/351 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 QFIGE-RAENTLLRLSKIGPKVVGSAANEQVAVQFLLSEIG-DIIDDARTDLYDIEKDV-QVASG 120
            :|:|| |.|:| :||:.:..:|.|| |.....||.:|.::. ..:|...||.:.:.... ..|..
Mouse   183 RFLGEGRMEDT-IRLTSLRERVAGS-ARMATLVQDILDKLSRQKLDHVWTDTHYVGLQFPDPAHA 245

  Fly   121 NYLLWSMVNVYQSIQNVVVKLSPK---------NATSEAALLINSHFDSVPGSSGAGDAGMMCVI 176
            |.|.|  |:...|:|..:....|:         |||.:   |:.:|:............|:....
Mouse   246 NTLHW--VDADGSVQEQLPLEDPEVYCPYSATGNATGK---LVYAHYGRSEDLQDLKAKGVELAG 305

  Fly   177 MLEVLRV-ITKYETPLTYSVVFLFNGAEENPLQGSHAFITQHPWAQNIRAVINLDSAGSGG---- 236
            .|.::|| ||.:...:..:..|...|....|.....:.....|...:.:||......|:|.
Mouse   306 SLLLVRVGITSFAQKVAVAQDFGAQGVLIYPDPSDFSQDPHKPGLSSHQAVYGHVHLGTGDPYTP 370

  Fly   237 -----REILF----QSG-PDHPWLMKYYGKNIVHPFASTIGEELFQ---NGFVPSETDYRVFRDY 288
                 .:..|    .|| |..|          ..|.::.|.::|.:   ....|.|..
Mouse   371 GFPSFNQTQFPPVESSGLPSIP----------AQPISADIADQLLRKLTGPVAPQEWK------- 418

  Fly   289 GHI--------PGLDMAQTLNGYVYHTKYDRFNLIPRRTYQLTGENILALVKALANAEEL----- 340
            ||:        ||.|:...:|.:...|..               .||.|.::..|..:..
Mouse   419 GHLSGSPYRLGPGPDLRLVVNNHRVSTPI---------------SNIFACIEGFAEPDHYVVIGA 468

  Fly   341 ------ENPSKYAEGHMIFFDMMGWF 360
                  ...:|.|.|..|..:::..|
Mouse   469 QRDAWGPGAAKSAVGTAILLELVRTF 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	71/351 (20%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
Tfr2	XP_030110515.1	PA_TfR	248..438	CDD:239043	40/211 (19%)
		M28_TfR	446..679	CDD:349946	9/64 (14%)
		TFR_dimer	706..830	CDD:367885
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900