DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9416 and naalad2

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_956571.1	Gene:	naalad2 / 393247	ZFINID:	ZDB-GENE-040426-1025	Length:	745	Species:	Danio rerio

Alignment Length:	334	Identity:	65/334 - (19%)
Similarity:	100/334 - (29%)	Gaps:	110/334 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IGWYWAPLFVSCWFLLFYLVVIPSFHRMPQLKTLEDERQQPGQFIGE-RAENT---LLRLSKIGP 77
            |||:..|..|:              |.......|.|       |:.| .|||.   |.:.:|: |
Zfish    27 IGWFARPSSVN--------------HERTSKSFLRD-------FMDEMHAENIKHHLRKFTKL-P 69

  Fly    78 KVVGSAAN----EQVAVQFLLSEIGDIIDDARTDLYDIEKDV-QVASGNYLLWSMVNVYQSIQNV 137
            .:.|:..|    ||:..:::  |.|  :|......||:.... ...:.||     :::...:.|.
Zfish    70 HLAGTQQNLNLAEQIRNEWM--EFG--LDSVELVPYDVLLSYPNKTNPNY-----ISIVDQLGNE 125

  Fly   138 VVKLSPKNATSEAALLINSHFDSVPGSSGAG-------------------------DAGMMCVIM 177
            :.|.|......|.   .....|.||..|...                         :.|:.|...
Zfish   126 IFKTSLAEPVPEG---YEDVADIVPPYSAFSAKGQPEDELVYVNYGRTEDFFKLERELGINCTGK 187

  Fly   178 LEVLRVITKYETPLTYSVVFLFNGAEENPLQGSHAFIT-QHP---WAQNIRAV---INLDSAGSG 235
            :.:.|          |..:|..|..:...|.|:...|. ..|   ||:::...   .||...|:.
Zfish   188 ILIAR----------YGKIFRGNKVKNAVLAGAKGIILFSDPADYWAEDVEPYPKGWNLPGGGAQ 242

  Fly   236 GREILFQSGPDHPWLMKYYGKNI----------------VHPFASTIGEELFQNGFVPSETD--- 281
            ...:|..:|...|....|..|..                |||........|.||...|:..|
Zfish   243 RGNVLNLNGAGDPLTPGYPAKEYTYRSSLEDAVGLPKIPVHPIGFHDAVHLLQNMGGPAPPDSWK 307

  Fly   282 ------YRV 284
                  ||:
Zfish   308 GALNVSYRI 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	57/294 (19%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
naalad2	NP_956571.1	Zinc_peptidase_like	47..>102	CDD:301362	16/66 (24%)
		PA_GCPII_like	108..333	CDD:239036	40/227 (18%)
		M28_PSMA_like	341..581	CDD:193568
		TFR_dimer	618..733	CDD:282153
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900