DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9416 and Ermp1

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	XP_006231303.1	Gene:	Ermp1 / 373544	RGDID:	727831	Length:	899	Species:	Rattus norvegicus

Alignment Length:	873	Identity:	273/873 - (31%)
Similarity:	443/873 - (50%)	Gaps:	94/873 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LLFYLVVIPSFHRMP-QLKTLEDERQQPGQFIGERAENTLLRLSKIGPKVVGSAANEQVAVQFLL 94
            |..||:.:.:..::. |...|.......|:|...:|...|..::.|||:..|||.||.:.||:||
  Rat    71 LALYLLALRALVQLSLQRLVLSRTSGLQGEFDARQARVYLEHITAIGPRTTGSAENEILTVQYLL 135

  Fly    95 SEIGDIIDDARTDLYDIEKDVQVASGNY---LLWSMVNVYQSIQNVVVKLSPKNATSEAALLINS 156
            .:| .:|::....|:.|..|||..:|::   .|....:.|.:|.||||||.|::. ::.|:|.|.
  Rat   136 EQI-TLIEEQSNSLHRISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPQDG-AKYAVLANC 198

  Fly   157 HFDSVPGSSGAGDAGMMCVIMLEVLRVITKYETPLTYSVVFLFNGAEENPLQGSHAFITQHPWAQ 221
            |||||..|.||.|..:.|.:|||||||:.....||.::|||||||||||.||.||.||||||||.
  Rat   199 HFDSVANSPGASDDAVSCAVMLEVLRVMAASPEPLQHAVVFLFNGAEENVLQASHGFITQHPWAS 263

  Fly   222 NIRAVINLDSAGSGGREILFQSGPDHPWLMKYYGKNIVHPFASTIGEELFQNGFVPSETDYRVFR 286
            .|||.|||::||.||:|::||:||::|||::.|.....|||||.:.:|:||:|.:||:||:|::|
  Rat   264 LIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYR 328

  Fly   287 DYGHIPGLDMAQTLNGYVYHTKYDRFNLIPRRTYQLTGENILALVKALANAEELENPSKYAEGHM 351
            |:|:|||:|:|...|||:||||||..:.|...:.|..|:||||::|.||.::.|.:.|:|..|.|
  Rat   329 DFGNIPGIDLAFIENGYIYHTKYDTADRILIDSIQRAGDNILAVLKYLATSDMLASSSEYRHGSM 393

  Fly   352 IFFDMMGWFFVYYPETTGIIINITVCVLVCVTIVLYIWMMSSSTGMFRRRIWAKF-------GIL 409
            :|||::|...:.||...|.|||    .:|.:.:|||:.         |:.:..|.       ..|
  Rat   394 VFFDVLGLLVIAYPSRVGSIIN----YMVVMAVVLYLG---------RKLLRPKHRNSNYVRDFL 445

  Fly   410 AALQLAGVALGIGL--VISIALFLDAVNLPMSWFSQNWMLFGLYFCPMIFGMGIVPAIYFSRT-- 470
            ..|.:..::....|  |:.||:|:..:...:||::.      .|....::|...|..|....|
  Rat   446 CGLGITFISWFTSLVTVLIIAVFVSLIGQSLSWYNY------FYIAVCLYGTATVAKIILIHTLA 504

  Fly   471 ------KEHGLPLG---YGIQLLMHSHCLILTIITAIMVSYSIRSAFVIMLCIGFYTLSVL-INL 525
                  ....|.||   :...|.:  ||..|..:||    ....|||:..:.:.|..|:.| :..
  Rat   505 KRFYYVNASDLYLGELFFDTSLFV--HCGFLVALTA----QGFCSAFMSAVWVAFPLLTKLCVYK 563

  Fly   526 VTKAHKTNFLWLIPHCICQVLPFMFYTYCCYAFYVVFVPMQGRE-CNTNPEILMGFFTALMVLLF 589
            ..|.|.....::..:.:...:|:::..|..:|.:.:|.|:.||. ....|::::....|:.|::.
  Rat   564 DFKKHGAKGRFIALYLLGMFIPYLYGLYLIWAVFEMFTPILGRSGSEIPPDVVLASILAVCVMIL 628

  Fly   590 APFLVPLFCLFRKS-KTIISMFGICTIVFIIFAATPIAFPYA---EKTAPQRFFAVHTARTFHNG 650
            :.:.:....|...: |||:::..:|.:.|::..:... |||:   :...|:|.|..|.:|||||.
  Rat   629 SSYFITFIYLVNSTKKTILTLILVCAVTFLLVCSGAF-FPYSSNPDSPKPKRVFLQHVSRTFHNL 692

  Fly   651 DPASTVSHKDSGYFVLPVDR------RPH--TVDDILFENTNFTKSERIDCDSEL-MCGFPIY-S 705
            :  .:|..:|||.::...|.      .||  .::|.:          |..|:... :||||.| .
  Rat   693 E--GSVVKRDSGIWINGFDYTGMSHVTPHIPEINDTI----------RAHCEENAPLCGFPWYLP 745

  Fly   706 SRWLNAVDNSYFVPGPEPNREYIPTLTILEKSSNSDTNIRFDLEISGPDHTSIFILPLNDSKLVD 770
            ..:|  :..::::|.||.:........::.|......:|:...|.:||.|.|.::.....|.|..
  Rat   746 VHFL--IRKNWYLPAPEISPRNPAHFRLVSKEKMPWDSIKLTFEATGPSHMSFYVRTHKGSTLSQ 808

  Fly   771 WSFIRDPLDGNVKP------PYYVYWSYALDPKPLQFSLEFEHEDPNWSGGTFKIALMGHRIHDD 829
            ||.      ||..|      .|:|::|:.|.....||.:|.:........|...:|:..|.:..:
  Rat   809 WSL------GNGIPVTSRGGDYFVFYSHGLQASAWQFWIEVQQVSEEQPEGMVTVAIAAHYLSGE 867

  Fly   830 MYITEDFREFLATFPPWAHVSSWLGSYN 857
            ...:.........||.|:..|:|:.:|:
  Rat   868 NKRSSQLDALKEKFPDWSFPSAWVSTYS 895

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	148/309 (48%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372	45/216 (21%)
Ermp1	XP_006231303.1	M28_Fxna_like	99..406	CDD:193497	148/308 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339531
Domainoid	1	1.000	242	1.000	Domainoid score	I2158
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	417	1.000	Inparanoid score	I1759
OMA	1	1.010	-	-		QHG59376
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm44686
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770