DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9416 and CG10073

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_001261090.1	Gene:	CG10073 / 37225	FlyBaseID:	FBgn0034440	Length:	881	Species:	Drosophila melanogaster

Alignment Length:	852	Identity:	335/852 - (39%)
Similarity:	493/852 - (57%)	Gaps:	27/852 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 WYWAPLFVSCWFLLFYLVVIPSFHRMPQLKTLEDERQQPGQFIGERAENTLLRLSKIGPKVVGSA 83
            ||.|..|:..|.|||..||:|.|:|:|...|:||..:  |.||.|||::.|.:|::||.|||||.
  Fly    44 WYLATGFLLFWALLFSAVVLPLFYRIPTGLTIEDASK--GVFIAERAQSNLYKLAEIGTKVVGSD 106

  Fly    84 ANEQVAVQFLLSEIGDIIDDARTDLYDIEKDVQVASGNYLLWSMVNVYQSIQNVVVKLSPKNATS 148
            .||...|.:|:..:.:|.::...|.:|||.|:|..||:|:.|:|||:||.:||:|:||||||.||
  Fly   107 NNENKTVDYLMGLVNEIQENCLDDYFDIEVDLQEVSGSYIHWTMVNMYQGVQNIVIKLSPKNTTS 171

  Fly   149 EAALLINSHFDSVPGSSGAGDAGMMCVIMLEVLRVITKYETPLTYSVVFLFNGAEENPLQGSHAF 213
            ...||:||||||.|.|..|||||.|.|.:||||||:...:..:.:.||||.|||||||||.||.|
  Fly   172 TTYLLVNSHFDSKPTSPSAGDAGQMVVAILEVLRVMCSTKQAIRHPVVFLLNGAEENPLQASHGF 236

  Fly   214 ITQHPWAQNIRAVINLDSAGSGGREILFQSGPDHPWLMKYYGKNIVHPFASTIGEELFQNGFVPS 278
            ||||.||:|.:.|:|||:||:||.:|:||:||:.|||::.|.:|..|..|:|:.||:||.|.:||
  Fly   237 ITQHKWAKNCKVVLNLDAAGNGGSDIVFQTGPNSPWLVEKYKENAPHYLATTMAEEIFQTGILPS 301

  Fly   279 ETDYRVFRDYGHIPGLDMAQTLNGYVYHTKYDRFNLIPRRTYQLTGENILALVKALANAEELENP 343
            :||:.:|..||::.|||||:.:||:.||||||:|:.|||.:.|.||:|:|.||:::||:.||:|.
  Fly   302 DTDFAIFVKYGNLIGLDMAKFINGFAYHTKYDQFSNIPRGSIQNTGDNLLGLVRSIANSTELDNT 366

  Fly   344 SKYAEGHMIFFDMMGWFFVYYPETTGIIINITVCVLVCVTIVLYIWMMSSSTGMFRRRIWAKFGI 408
            ..||.||.||||::|.:|:.|.|:.|:|:|.:|..:..|.|.|.||..||.:.:....:...|.:
  Fly   367 EAYATGHAIFFDVLGLYFISYTESNGVILNYSVAGVALVLIFLSIWRTSSISRVSIGHVLCWFIL 431

  Fly   409 LAALQLAGVALGIGLVISIALFLDAVNLPMSWFSQNWMLFGLYFCPMIFGMGIVPAIYFSRTKEH 473
            :..||:....||:||.|.:|...|...|.:::||...:|.|||.||.:.|:.:...||....:..
  Fly   432 IFVLQIIAFVLGLGLPIVVAYVFDKYGLSITYFSTPVLLIGLYICPSLLGLSLPSYIYLKLQRSE 496

  Fly   474 GLPLGYGIQLLMHSHCLILTIITAIMVSYSIRSAFVIMLCIGFYTLSVLINLVTKAHKTNFLWLI 538
            .:.....:||::|.|..:|.|:...:..|.:|||:|....:.||.:.:.:||:|..|...|.|..
  Fly   497 KVGFAQHLQLVLHGHAAVLAILDIGLTVYGLRSAYVPTWTLIFYVIPLAVNLLTTLHDRGFSWTG 561

  Fly   539 PHCICQVLPFMFYTYCCYAFYVVFVPMQGRECN-TNPEILMGFFTALMVLLFAPFLVPLFCLFRK 602
            ...|.||:||::.:|..|.|.|..:||.||... |||::::....||..:|...|::||..:||:
  Fly   562 VLKIFQVVPFLYNSYLIYCFVVTLIPMMGRFGRATNPDLIISALCALGTILALGFVIPLVNMFRR 626

  Fly   603 -SKTIISMFGICTIVFIIFAATPIAFPYAEKTAPQRFFAVHTARTFHNGDPASTVSHKDSGYFVL 666
             |..::::..|..:.....::|.|.|||..||..||...:|..|.|:..|  .||...||||...
  Fly   627 PSLILLTLLAISAVTIYTASSTQIGFPYRPKTNVQRLPYLHVRRIFYEYD--GTVVKNDSGYLFN 689

  Fly   667 PVDRRPHTVDDILFENTNFTKSERIDCDSELMCGFPIYSSRWL-NAVDNSYFVPGPEPNREYIPT 730
            ..|||......:...||....|...|||:.:|||||:|..||: |.:...:.....|....|.|.
  Fly   690 FQDRRGPAPLKLSKLNTTGLVSIAADCDTVMMCGFPLYDHRWVKNRLQIMWLPREEEIITPYEPK 754

  Fly   731 LTILEKSSNSDTNIRFDLEISGPDHTSIFILPLNDSKLVDWSFIRDPLDGNVKPPYYV------- 788
            |.:|.|:...:..:|.:.:.:..||.|:||.||.|..:.:||.          |..|:
  Fly   755 LELLSKTELGNNTLRMNFQSATTDHASVFIQPLEDVIISNWSL----------PTSYIGQQDTSH 809

  Fly   789 -YWSYALDPKPLQFSLEFEHEDPNWSGGTFKIALMGHRIHDDMYITEDFREFLATFPPWAHVSSW 852
             |:||..:...|.|.::|...|.:::....:|.|..|.|.:......  :||....|.:|....|
  Fly   810 MYFSYGKNNTALTFFIDFYKLDADFAVPLCQIGLAVHFIGNKGDAIS--QEFAKKIPSFAAAVDW 872

  Fly   853 LGSYNSW 859
            ..||..:
  Fly   873 PASYQRY 879

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	164/306 (54%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372	61/202 (30%)
CG10073	NP_001261090.1	M28_Fxna_like	80..387	CDD:193497	164/308 (53%)
CG10073	NP_001261090.1	NrfD	398..638	CDD:304401	74/239 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446916
Domainoid	1	1.000	161	1.000	Domainoid score	I1255
eggNOG	1	0.900	-	-		E1_COG2234
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	359	1.000	Inparanoid score	I1290
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D14040at33392
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm25001
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	P	PTHR12147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X435
	12	11.800