DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9416 and CG13160

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_001260918.1	Gene:	CG13160 / 36343	FlyBaseID:	FBgn0033720	Length:	875	Species:	Drosophila melanogaster

Alignment Length:	873	Identity:	337/873 - (38%)
Similarity:	528/873 - (60%)	Gaps:	39/873 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ENMKIIYNRSKI-----GWYWAPLFVSCWFLLFYLVVIPSFHRMPQLKTLEDERQQPGQFIGERA 65
            ||:.|..:..||     .||:||:::..|..||:.|:.|.|..:|....:.:|..:||||:.|||
  Fly    15 ENLIIEVDEDKIRCKQYSWYFAPIYLLFWVGLFFAVIYPLFQALPTGIKISEEADKPGQFVAERA 79

  Fly    66 ENTLLRLSKIGPKVVGSAANEQVAVQFLLSEIGDIIDDARTDLYDIEKDVQVASGNYLLWSMVNV 130
            :..||::|::||:|||...||...|..||:||..:....|.|:|::|.:||.|||:||:..:.|.
  Fly    80 QEILLQISRLGPRVVGDVDNEVTVVNLLLAEIEKVRQVLRDDVYEMEVEVQRASGSYLIKGLTNH 144

  Fly   131 YQSIQNVVVKLSPKNATSEAALLINSHFDSVPGSSGAGDAGMMCVIMLEVLRVITKYETPLTYSV 195
            ||.:|||:|:||.|::.|.:.||:|||:|:.|||.||||...|.|:||||||::.....|..:.:
  Fly   145 YQGVQNVIVRLSTKSSNSTSYLLVNSHYDTKPGSPGAGDDAAMVVVMLEVLRLVAVSGDPFLHPI 209

  Fly   196 VFLFNGAEENPLQGSHAFITQHPWAQNIRAVINLDSAGSGGREILFQSGPDHPWLMKYYGKNIVH 260
            :||||||||.|:||||.|||||.||.|.:|::||||||:|||::|||.||:|||||::|..:..|
  Fly   210 IFLFNGAEEQPMQGSHGFITQHRWAANCKALLNLDSAGAGGRDLLFQGGPNHPWLMEHYRNSAPH 274

  Fly   261 PFASTIGEELFQNGFVPSETDYRVFRDYGHIPGLDMAQTLNGYVYHTKYDRFNLIPRRTYQLTGE 325
            |||:|..||:|:.|.:||:||:|:|||:|.:||||||...||:|||||:||:.:|...:.|.:|:
  Fly   275 PFATTTAEEMFEAGIIPSDTDFRIFRDFGVVPGLDMAGVYNGFVYHTKFDRYAVISLDSLQNSGD 339

  Fly   326 NILALVKALANAEELENPSKYAEGHMIFFDMMGWFFVYYPETTGIIINI----TVCVLVCVTIVL 386
            |:||||.:::||||:.:...:|.||.:|||.:|.|||:|.|:|.:.:|:    ...:|||::
  Fly   340 NLLALVWSISNAEEMYDTEAHAAGHAVFFDFIGLFFVHYQESTSLALNLFFSFGAILLVCIS--- 401

  Fly   387 YIWMMSSSTGMFRRRIWAKFGILAALQLAGVALGIGLVISIALFLDAVNLPMSWFSQNWMLFGLY 451
             :|.||..||.........||:|..|.|||..|.:...:.:|.|.|..|..:::||.:|::.|||
  Fly   402 -LWRMSRVTGQTMGTYAGVFGLLFLLALAGALLAVAFPLLMATFYDWGNRTLTYFSNSWLVIGLY 465

  Fly   452 FCPMIFGMGIVPAIYFSRTKEHGLPLGYGIQLLMHSHCLILTIITAIMVSYSIRSAFVIMLCIGF 516
            .||.:.|:.:...:|.:.||.:.:|..|.:.::.|::|::|.|:.....:...|||::.::.:.|
  Fly   466 ICPSVIGLVLPMTLYLTHTKCNKIPHTYYLHIVGHANCVLLAILCLGATALKYRSAYLFLISLIF 530

  Fly   517 YTLSVLINLVTKAHKTNFLWLIPHCICQVLPFMFYTYCCYAFYVVFVPMQGR-ECNTNPEILMGF 580
            |..:::|||:|:.|...:||.:...:.|::||:::.|..:.|.::.:||.|| ..:|||:||:|.
  Fly   531 YVAALIINLLTRLHCRGYLWSLVLIVFQIIPFIYHAYLFHMFILILIPMTGRFGVSTNPDILIGA 595

  Fly   581 FTALMVLLFAPFLVPLFCLFRKSKTIISMFGICTIVFIIFAATPIAFPYAEKTAPQR--FFAVHT 643
            ......:|...|..||..:||:...::....:...:|.:.|.:.:.|||..||...|  |..||.
  Fly   596 LCGFGTILALSFAAPLINVFRRPNCMLGGLALVMFIFCMIAVSDVGFPYRPKTNVMRADFMQVHR 660

  Fly   644 ARTFHNGDPASTVSHKDSGYFVLPVDRRPHTVDDILFENTNFTKSERI--DCDSELMCGFPIYSS 706
            ....:||    ::||:||||:....||.....   |.::.|.|...|:  |||||||||.|.|
  Fly   661 KFFEYNG----SISHEDSGYYFHLGDRNKEAP---LRDHMNLTNLVRLGEDCDSELMCGIPCY-- 716

  Fly   707 RWLNAVDNSYFVPGPEPNREYIPTLTILEKSS----NSDTNIRFDLEISGPDHTSIFILPLNDSK 767
            |:.:|.:::.::...||..  :|..|:||..|    :....:|::..::||.:..:|..||:..|
  Fly   717 RYCSAREHALWLAREEPVE--LPYPTVLEFLSKTVLSGGYQVRYEFRLTGPPNMGLFFKPLDGVK 779

  Fly   768 LVDWSFIRDPLD--GNVKPPYYVYWSYALDPKPLQFSLEFEHEDPNWSGGTFKIALMGHRI--HD 828
            |:.|:|....||  ...:||..|..:|.:|..|::|.:|...:|.|::...|::.:.||.:  ||
  Fly   780 LLRWTFAPAMLDNPATYRPPLEVMLTYGIDNTPIEFFVELSKDDGNFNEPVFEMGVSGHYVSPHD 844

  Fly   829 DMYITEDFREFLATFPPWAHVSSWLGSY 856
            ......  .|||||.|.:|....|..||
  Fly   845 KRDALS--LEFLATLPDFAFSMEWPSSY 870

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	163/306 (53%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372	57/201 (28%)
CG13160	NP_001260918.1	M28_Fxna_like	71..378	CDD:193497	163/306 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446918
Domainoid	1	1.000	161	1.000	Domainoid score	I1255
eggNOG	1	0.900	-	-		E1_COG2234
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	212	1.000	Inparanoid score	I1244
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D14040at33392
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm25001
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	P	PTHR12147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X435
	12	11.800