DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9416 and Naalad2

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_001100272.1	Gene:	Naalad2 / 300384	RGDID:	1305872	Length:	778	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	81/359 - (22%)
Similarity:	110/359 - (30%)	Gaps:	135/359 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 IGPKVVGSAANEQVAVQFLLSEIGDIIDDARTDLYDIEKDVQVASGNYLLWSMVNVYQSIQNVVV 139
            |||...||..:.:|                |..:::|.|             :..:|..|..:..
  Rat   357 IGPGFSGSEYSRKV----------------RMHVHNINK-------------ITRIYNVIGTIRG 392

  Fly   140 KLSPKNATSEAALLINSHFDSVPGSSGAGDAGMMCVIMLEVLRVITKYET----PLTYSVVFLFN 200
            ...|     :..:::..|.||  ...|..|......::.|:.|...|...    | ..:::|...
  Rat   393 STEP-----DRYVILGGHRDS--WVFGGIDPTTGTAVLQEIARSFGKLVNGGWKP-RRTIIFASW 449

  Fly   201 GAEENPLQGSHAFITQHPWA-QNIR-------AVINLDSAGSG-------------------GRE 238
            .|||..|.||    |:  || :|.:       |.||.|||..|                   .||
  Rat   450 DAEEFGLLGS----TE--WAEENAKILQERSIAYINSDSAIEGNYTLRVDCTPLLHQLVYKVARE 508

  Fly   239 ILFQSGPD---------HPWLMKYYG-KNIVHPFASTIG-----EELFQN-GFVPSETDY---RV 284
            |   |.||         ..||.|... :|...|..:.:|     |..||. |.......|   :.
  Rat   509 I---SSPDDGFESKSLYESWLEKDPSPENKERPRINKLGSGSDFEAYFQRLGIASGRARYTKNKK 570

  Fly   285 FRDYGHIPGLDMAQTLNGYVYHTKYDRFNLIPR----------RTYQLTGE-------------N 326
            ...|...|           ||||.|:.|.|:..          ...||.|.             |
  Rat   571 TDKYSSYP-----------VYHTIYETFELVQNFYDPTFKKQLSVAQLRGALVYELADCVVIPFN 624

  Fly   327 ILALVKALAN-AEELENPSK----YAEGHMIFFD 355
            |....|||.| |..:.|.||    ....|.:.||
  Rat   625 IQDYAKALKNYAASIFNLSKKHDQQLRDHGVSFD 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	81/359 (23%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
Naalad2	NP_001100272.1	Zinc_peptidase_like	86..>143	CDD:417508
		PA_GCPII_like	148..374	CDD:239036	7/32 (22%)
		M28_PSMA_like	<382..623	CDD:349942	59/268 (22%)
		TFR_dimer	655..774	CDD:398094	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900