DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9416 and Tfr2

DIOPT Version :9

Sequence 1:	NP_001261088.1	Gene:	CG9416 / 37223	FlyBaseID:	FBgn0034438	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	XP_006249178.1	Gene:	Tfr2 / 288562	RGDID:	1310152	Length:	838	Species:	Rattus norvegicus

Alignment Length:	236	Identity:	46/236 - (19%)
Similarity:	92/236 - (38%)	Gaps:	63/236 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 LLINSHFDSVPGSS--------------------------GAGDAGMMCVIMLEVLRVITKYET- 189
            |::|:|..|.|.|:                          ||..:.:...|:||::|..:...:
  Rat   434 LVVNNHRTSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSS 498

  Fly   190 ---PLTYSVVFLFNGAEENPLQGSHAFITQHPWAQNIRAV--INLDSA--GSGG----------- 236
               |....:...::|.:...: |:..::..:....:::||  ::||::  |.|.
  Rat   499 GFRPRRSLLFISWDGGDFGSV-GATEWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKTSPLLVS 562

  Fly   237 --REILFQ-SGPDHPWLMKYYGKNIVHPFASTIGEELFQNGFVPSETDYRVFRDYGHIPGLDMAQ 298
              ..||.| ..|:|.....|......||   :...|:.|.  :|.::....|..:..:|.::.:.
  Rat   563 LIENILKQVDSPNHSGQTLYDQVAFTHP---SWDAEVIQP--LPMDSSAYSFTAFAGVPAVEFSF 622

  Fly   299 TLNGYVY---HTKYDRF-NLIPRRTYQLTGENILALVKALA 335
            ..:..||   |||.|.: ||     :::....:.|:|.|:|
  Rat   623 MEDDRVYPFLHTKEDTYENL-----HKMLRGRLPAVVLAVA 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9416	NP_001261088.1	M28_Fxna_like	57..364	CDD:193497	46/236 (19%)
CG9416	NP_001261088.1	MFS	423..>624	CDD:304372
Tfr2	XP_006249178.1	PA_TfR	246..436	CDD:239043	1/1 (100%)
		M28_TfR	444..677	CDD:193572	42/226 (19%)
		TFR_dimer	709..828	CDD:282153
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900