Protein Alignment CG10051 and PFF1

DIOPT Version :9

• Sequence 1: NP_611414.1
• Gene: CG10051 / 37222
• FlyBaseID: FBgn0034437
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_009630.3
• Gene: PFF1 / 852366
• SGDID: S000000278
• Length: 976
• Species: Saccharomyces cerevisiae
• Alignment Length: 903
• Identity: 187/903 - (20%)
• Similarity: 323/903 - (35%)
• Gaps: 293/903 - (32%)

  Fly    47 YSYPKMLY----------QSEEALHPD-KFIGERAMRQLAEYSAIGNKMSGSINNEVHTINFLLR 100
            ||...:||          ..:|..||: ..:.|.|...|...:|..:..:...|::||  ::||:
Yeast    26 YSIITLLYIFDHERYKLNLPKEDEHPEFNDLLETAWGDLQIITASFHPYTSKENDKVH--DYLLK 88

  Fly   101 EIQKI------------KDEARLDLYDIEVDTQYSSGAFHLWGMTISYTNLSNVVVKISQKSSDN 153
            .:.:|            |:..|..|:. :.|....|..|    ..::|...||::||:..|:.:.
Yeast    89 RVLEITGNSSFASVSDDKESERSILFQ-QQDPFNESSRF----SRVTYFESSNILVKLEGKNPEE 148

  Fly   154 ENYLLVNSHYDSEVQTPAAGDDGVMVVVMLETLR--VISRSERTLTHPVVFLFNGAEEACMLGSH 216
            |. ||:::|:||......|.|||:.||.:|..|:  :..|..|||    :|.||..||..:||:.
Yeast   149 EG-LLLSAHFDSVPTGYGATDDGMGVVSLLANLKYHIKHRPNRTL----IFNFNNNEEFGLLGAS 208

  Fly   217 GFITQHKWSKNCKALVNLDSTGAGGREVLFQTGPNHPWLAKYYQASV-PHPYAQTLAEELFQHNF 280
            .:. .|.||...|.::||:.|||||:.|||:|....  .|:.||.|| .:|:..::.::.|...:
Yeast   209 TYF-DHSWSNLTKYVINLEGTGAGGKAVLFRTSDTS--TARIYQQSVKENPFGNSIYQQGFYSRY 270

  Fly   281 IPSDTDFRIFRDYGGVPGLDMASVMNGYVYHTEFDNFKNVEYGTYQSTGENVLPLIW-------- 337
            :.|:||::|:.: .|:.|.|:|......:|||..|   :::|.:..|        :|
Yeast   271 VRSETDYKIYEE-NGMRGWDVAFYKPRNLYHTIKD---SIQYTSKAS--------LWHMLHTSLQ 323

  Fly   338 --ALANAPELDNTTAYEKGHTVYYDFLGWFMMTYTESVSIAINVVVSVAAFICIGTSVYIMTLDN 400
              |...:..||..   ::....|:||:|
Yeast   324 LSAYVASNSLDTA---DQTPACYFDFIG------------------------------------- 348

  Fly   401 GADAPKAVVLRFAIIFLVQAGTLFVACGLTLLVAVFMQGVGL------AESWYYGKWMAFGLYFC 459
                     |:|   |::.|.|||....:.|||:..: .:||      ..:|....|:::..:
Yeast   349 ---------LKF---FVISAKTLFYWNCIFLLVSPVV-AIGLYLISRDRMTWKSYSWLSWTRF-- 398

  Fly   460 TLFFAFGILPATYIGFTKRKTNMKLDQTIACFMHAQCILLALLCIIMTIMG---IRSSYFPMVGI 521
            .|..|.||                                    |:..:..   |||:.......
Yeast   399 PLSLAAGI------------------------------------IVQKLFSNDIIRSNPLTFSRN 427

  Fly   522 FFYAISV-LVQIVLKLTLKKSYFVTVHLLFQVLPFFF-----------YTYICYATLVTFVPMEG 574
            :|:.||. ..|::.          |.::|.....|||           ..:|...|::.|.
Yeast   428 YFWPISAFFTQVIF----------TSYVLINCSNFFFPCADMKSLSIIELFIILWTILLFT---- 478

  Fly   575 RDGPESSPDIMISVFIIATAINYAGFVIPIMHKFRKPKIIFSSFGVITIIFIILACTSAGFPFVK 639
                        |..:.::...|.|..         |..||.....|..|..:|| .:.|....|
Yeast   479 ------------SKLLYSSDYRYTGLY---------PLSIFFLLSTIAAILRLLA-LALGMRTRK 521

  Fly   640 QLAPQ-----RYYVLHTQRTFHNLDGTSKQDSGYYIQPVDTRLHELDDTTFKNAEPESWTAATCA 699
            :|..:     ..|..|:|..... ||....:     ||.|......||    .|..:....:|.:
Yeast   522 RLGRECRDHHSNYSSHSQIDMER-DGQENLE-----QPQDQLTSSQDD----QASIQDDNVSTTS 576

  Fly   700 AEPYCG-----------------LPLYSGR--------------WIEWKDSARWIYSSPPVIP-- 731
            |.|...                 :||..|.              .:|:.|.| ||.....::|
Yeast   577 AGPSHNVDEDHGMDSSSQQHDERVPLLKGSNSMEEGLSTRENSLKLEYTDYA-WIIQFLLIVPIP 640

  Fly   732 -------MNINLTQLSKQSLDGNKVRYE---YNLRASDRVMMYIDPLDNVKVTDWSFDHTPLVEK 786
                   :::.:..|:....:|:|..::   :.:..|..:.:.|.|. ..||...:...|.|:
Yeast   641 SFILFNSVDVIMDALNHTVQEGSKATFDVLRFGMVGSILIALPILPF-FYKVNYITISLTALL-- 702

  Fly   787 HTPPYLIYAIYSQTEEP--------LNFWVELEHEEGNT--------DGPYMKLVVSE 828
                :||.|..:....|        :.|...::..:||.        :|.::|.::.:
Yeast   703 ----FLISASKTLLVHPFTNSNPLKVRFSQNIDLSQGNAASVHVLGREGNFLKPMLQD 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10051	NP_611414.1	M28_Fxna_like	62..369	CDD:193497	92/332 (28%)
		MATE_like	361..>604	CDD:298879	39/263 (15%)
PFF1	NP_009630.3	M28_Fxna_like	50..354	CDD:349872	96/382 (25%)
		DUF2189	366..>443	CDD:413262	19/125 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343302
Domainoid	1	1.000	99	1.000	Domainoid score	I1571
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm46574
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1738
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870