DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10051 and AT1G67420

DIOPT Version :9

Sequence 1:	NP_611414.1	Gene:	CG10051 / 37222	FlyBaseID:	FBgn0034437	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001321979.1	Gene:	AT1G67420 / 843062	AraportID:	AT1G67420	Length:	943	Species:	Arabidopsis thaliana

Alignment Length:	942	Identity:	238/942 - (25%)
Similarity:	401/942 - (42%)	Gaps:	177/942 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 AFALFYAAVLPSFYSYPKMLYQSE-EALHP-DKFIGERA---MRQLAEYSAIGNKMSGSIN-NEV 92
            :....||.:....||...|.:.|. .|..| ::|...||   :|.|||  .|..:..|... .|.
plant    68 SLVFIYALMSAIVYSVLHMKFISPLPANAPLERFSEARAVEHIRVLAE--EIDGRQEGRPGLKEA 130

  Fly    93 HTINFLLREIQKIKDEA----RLDLYDIEVDTQYSSGAFHLWGMTISYTNLSNVVVKISQKSS-D 152
            .|  ::..:::.:|:.|    |:::.:.:||..:|. .|....:::.|.|.:|::::||..:| |
plant   131 AT--YIKSQLEMVKERAGPNLRVEVEETQVDGSFSM-MFLGHSISLGYRNHTNILMRISSMNSLD 192

  Fly   153 NENYLLVNSHYDSEVQTPAAGDDGVMVVVMLETLRVISRSERTLTHPVVFLFNGAEEACMLGSHG 217
            .:..:|:|:||||.|.:|.|||.|..|..:||..|::..|......||:||||||||..||||||
plant   193 TDASVLMNAHYDSPVNSPGAGDCGSCVASLLELARLVVDSGWVPPQPVIFLFNGAEELFMLGSHG 257

  Fly   218 FITQHKWSKNCKALVNLDSTGAGGREVLFQTGPNHPWLAKYYQASVPHPYAQTLAEELFQHNFIP 282
            |:|:||......|.:|::::|.||.:::.|:||. .|.:..|..:..:|.||:.|:::|.  .||
plant   258 FMTKHKLKDTIGAFINVEASGTGGIDLVCQSGPG-SWPSYVYSQAAVYPMAQSSAQDVFP--VIP 319

  Fly   283 SDTDFRIF-RDYGGVPGLDMASVMNGYVYHTEFDNFKNVEYGTYQSTGENVLPLIWALANAPELD 346
            .|||:|:| .||..:||||:..::.||.|||.||....:..|:.|:.|||::.::.|.|::..|.
plant   320 GDTDYRMFAEDYADIPGLDIIFLLGGYYYHTTFDTVDRIVPGSMQARGENLISVLKAFASSSRLK 384

  Fly   347 ------------NTTAYEKGHTVYYDFLGWFMMTYTESVSIAINVVVSVAAFICIGTSVYIMTLD 399
                        |:...|:  .|::|:|.|||:.|...|:..:: .:..|.|:|:...:|:|
plant   385 VASERKTLDVDANSDMVER--AVFFDYLTWFMVFYPRRVAFVLH-NIPAALFLCVPFFLYMM--- 443

  Fly   400 NGADAPKAVVLRFAIIFLVQAGTLFVACGLTL------LVAVFMQGVGLAESWYYGKWMAFGLYF 458
               |.....:|.|...|.  .|.:....|:.|      |.||.........||:...::||.::.
plant   444 ---DPRTHPLLSFFWAFF--KGVMHHFAGILLGVIVPVLFAVIRLFFAYPMSWFAHSYLAFLMFI 503

  Fly   459 CTLFFAFGILP-------ATYIGFTKRKTNMKLDQTIACFMHAQCILLALLCIIMTIMGIRSSYF 516
            ...||.. ::|       :.:.|.:.:|. ||::.:............|.........|:...:.
plant   504 PCSFFGL-LIPRAISDRVSHFQGVSSKKI-MKVEPSDEARFWGAFGFYAFATSAYFFAGLNGGFM 566

  Fly   517 PMVGIFFYAISVLVQIVLKLTLKKSY---------FVTVHLLFQVLPFFFYTYICYATLVTFVPM 572
                .|..:||:|:..:......|||         |..:.|    :|...|: :.:..::|.:.:
plant   567 ----TFVISISMLLGWIAFYLSVKSYGYNSIKSPMFYVIAL----VPCLLYS-LYFGGILTLLLI 622

  Fly   573 E--GRDGPESSP------DIMISVFI-IATAINYAGFVIPIMHKFRKPKIIFSSFGVITIIFIIL 628
            |  |..|....|      |:.::..| |.|.: ..|.:|||..::.....|.......|:  ::|
plant   623 EKTGMMGAIPPPYGFYLADVAVAAVIGIVTGL-CLGPIIPICDRWLAKSSILKFLLHFTV--VML 684

  Fly   629 ACTSAGFPFVKQLAPQRYYVLHTQRTFHNLDGTSKQDSGYYIQPVDT---------------RLH 678
            |.:|..||:.|. ||:|..:.|   ||.:..|.....|.|.:..:|:               .||
plant   685 AVSSQFFPYSKD-APKRVVLQH---TFISTGGNEITGSSYDLAVIDSNSMEFIFKHAPEVAKELH 745

  Fly   679 ELDDTTFKNAE---PESWTA-----------------ATCAAEPYCGLPLYSGR--WIEWKDSAR 721
            .....:..|||   .|:|.|                 |....|.|...||....  ...:::..|
plant   746 VGPSFSLGNAEASPQEAWMALFPISCVLTTNGRFPAKANNILERYSQFPLLQAHKPQTTFENGTR 810

  Fly   722 WIYSSPPVIPMNINLTQLSKQSLDGNKVRYEYNLRASDRVMMYID-----PLDNVKVT------- 774
            .::     :.:::.|..|.|:.|               .|::.|:     .|:.:.||
plant   811 RVH-----LELSLGLVGLHKELL---------------LVLLVINYSICRSLEEIWVTVLNITGP 855

  Fly   775 --DWSF----DHTPLVEKHTPPYLIYAIYSQTEEPLNFWVELEHEEGNTDGPYMKLVVSEHFQYH 833
              .|||    ...|.:....||..|..:...::|..|||:|...||          .|.......
plant   856 LSGWSFADGKPPAPELPPGGPPSYILRLSGNSDEKWNFWLEASSEE----------EVRVDVAVL 910

  Fly   834 PEYYTEEYKEFLATFPDWTYTTDWFSALESWI 865
            .:...||.......||.|:....:.|.|.:::
plant   911 DQRLDEETIHLKGLFPKWSDVIAYTSFLSTYL 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10051	NP_611414.1	M28_Fxna_like	62..369	CDD:193497	114/329 (35%)
CG10051	NP_611414.1	MATE_like	361..>604	CDD:298879	56/273 (21%)
AT1G67420	NP_001321979.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1262
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	212	1.000	Inparanoid score	I1244
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248924at2759
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm3269
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.830