DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10051 and Naaladl1

DIOPT Version :9

Sequence 1:	NP_611414.1	Gene:	CG10051 / 37222	FlyBaseID:	FBgn0034437	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_113947.1	Gene:	Naaladl1 / 83568	RGDID:	620987	Length:	745	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	80/370 - (21%)
Similarity:	139/370 - (37%)	Gaps:	95/370 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 NLSNVVVKISQKSSDNENYLLVNSHYDSEVQ---TPAAGDDGVMVVVMLETLRVIS--------R 191
            |.|| |:.|.|.:.:.:.|::..:|.||.|.   .|::|     ..|:||..||:.        |
  Rat   350 NSSN-VLGIIQGAVEPDRYVIYGNHRDSWVHGAVDPSSG-----TAVLLEISRVLGTLLKKGTWR 408

  Fly   192 SERTLTHPVVFLFNGAEEACMLGSHGFITQ--HKWSKNCKALVNLD-------STGAGG----RE 243
            ..|:    ::|...||||..::||..|..:  .|..:.....:|:|       :..|.|    :.
  Rat   409 PRRS----IIFASWGAEEFGLIGSTEFTEEFLSKLQERTVTYINVDISVFSNATLRAQGTPPVQS 469

  Fly   244 VLFQ-----TGPNHPWLA------KYYQASVPHPYAQTLAEELFQHNFIPS------DTDFRIFR 291
            |:|.     :.|....|:      :|...|.|            .:..:||      .:|:..|.
  Rat   470 VIFSATKEISAPGSSGLSIYDNWIRYTNRSSP------------VYGLVPSMGTLGAGSDYASFI 522

  Fly   292 DYGGVPGLDMA--------SVMNGYVYHTEFDNFKNVE------YGTYQSTGENVLPLIWALANA 342
            .:.|:..:|:|        |......|||.||.|..||      :.::|:.......::..|:::
  Rat   523 HFLGITSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRLSDS 587

  Fly   343 PELD-NTTAYEKGHTVYYDFLGWFMMTYTESVSIAIN-VVVSVAAFICIGTSV--YIMTLDNGAD 403
            ..|. |.:.|.:....:.......:....||.:|::. :|.:|..|.....::  :|:||...:.
  Rat   588 LFLPLNVSDYSETLQSFLQAAQENLGALLESHNISLGPLVTAVEKFKAAAAALNQHILTLQKSSP 652

  Fly   404 APKAVVLRFAIIFLVQAGTLFVACGLTLLVAVFMQGVGLAESWYY 448
            .|..|.:              |...|.||...|:......|..||
  Rat   653 DPLQVRM--------------VNDQLMLLERAFLNPRAFPEERYY 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10051	NP_611414.1	M28_Fxna_like	62..369	CDD:193497	61/286 (21%)
CG10051	NP_611414.1	MATE_like	361..>604	CDD:298879	19/91 (21%)
Naaladl1	NP_113947.1	Zinc_peptidase_like	53..>126	CDD:387401
		PA_GCPII_like	119..331	CDD:239036
		M28_PSMA_like	<353..592	CDD:349942	57/260 (22%)
		TFR_dimer	621..740	CDD:367885	17/77 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900