DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10051 and AT5G20660

DIOPT Version :9

Sequence 1:	NP_611414.1	Gene:	CG10051 / 37222	FlyBaseID:	FBgn0034437	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_197566.1	Gene:	AT5G20660 / 832189	AraportID:	AT5G20660	Length:	910	Species:	Arabidopsis thaliana

Alignment Length:	985	Identity:	227/985 - (23%)
Similarity:	392/985 - (39%)	Gaps:	222/985 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DITEEKDGGKSRD--------------------KKW----------PWFGAPIYAAAAFALFYAA 41
            |:||.....|..|                    |.|          .||
plant    10 DLTEPSSSSKETDASSDKDALDKEVQADVKRSGKVWLSVLILITYSSWF---------------- 58

  Fly    42 VLPSFYSY-----PKML---------YQSEEALHPDKFIGERAMRQLAEYSAIGNKMSGSINNEV 92
                .|:|     ||.|         :...||:   |.:  :|:.|...:....:.:       |
plant    59 ----VYNYQLGNLPKPLTAKQAGKRGFSEIEAI---KHV--KALTQFGPHPVSSDAL-------V 107

  Fly    93 HTINFLLREIQKIKDEARLDLYDIEVD--------TQYSSGAFHLWGMTISYTNLSNVVVKISQK 149
            |.:.::|.|::|:|:.|..:: |:.||        .:...|.|.  |.::.|:::|::|::|..|
plant   108 HALEYVLAEVEKVKETAHWEV-DVNVDFFESKFGVNRLVGGLFK--GKSLVYSDISHIVLRILPK 169

  Fly   150 --SSDNENYLLVNSHYDSEVQTPAAGDDGVMVVVMLETLRVISRSERTLTHPVVFLFNGAEEACM 212
              |...:|.:||:||.|:...|..|||....|.||||..|..|:|.....:.::||||..||..:
plant   170 YESDAGDNAILVSSHIDTVFTTGGAGDCSSCVAVMLELARSASQSAHGFKNSIIFLFNTGEEEGL 234

  Fly   213 LGSHGFITQHKWSKNCKALVNLDSTGAGGREVLFQTGPNHPWLAKYYQASVPHPYAQTLAEELFQ 277
            .|:|.|||||.||...:..::|::.|.||:..:||.||: ||..:.:..:..:|..|.:.::||.
plant   235 NGAHSFITQHPWSSTVRLAIDLEAMGTGGKSSIFQAGPS-PWAIENFALAAKYPSGQIIGQDLFT 298

  Fly   278 HNFIPSDTDFRIFRDYGGVPGLDMASVMNGYVYHTEFDNFKNVEYGTYQSTGENVLPLIWALANA 342
            ...|.|.|||:::::..|:.|||.|...|..||||:.|..:.::.|:.|..|||:|..:..:|::
plant   299 SGIIKSATDFQVYKEVAGLSGLDFAFADNTAVYHTKNDKIELIKPGSLQHLGENMLAFLLRVASS 363

  Fly   343 PEL--DNTTAYEK----GHTVYYDFLGWFMMTYTESVSIAINVVVSVAAFICIGTSVYIMTLDNG 401
            .:|  |.|...|:    ...||:|.||.:|:.|.:|::..:.|.|.:.:.:     ::::::..|
plant   364 SDLPKDKTLQGEERSNPDSAVYFDVLGKYMIVYRQSLATMLYVSVIMQSIL-----IWVLSVFMG 423

  Fly   402 ADAPKAVVLRFAIIFLVQAGTLFVACGLTLLVAVFMQGVGLAE-SWYYGKWMAFGLYFCTLFFAF 465
            . .|..|.|..:.:.::.:....||  .::.||..:..:..:. .:....||..||:.....  .
plant   424 G-YPAVVSLILSCLSIILSWIFSVA--FSVAVAFILPWISSSPVPFASNPWMVVGLFVSPAI--L 483

  Fly   466 GILPATYIGF------------TKRKTNMKLDQTIACFMHAQ-----------CILLALLCIIMT 507
            |.:...::.|            .|.:.:.:|...:| .:.|:           .:||||    .|
plant   484 GSISGQHVAFIFLRKKSSNRNSNKMQVSPRLRDNLA-RLEAERWLFKSGFIQWLVLLAL----GT 543

  Fly   508 IMGIRSSYFPMVGIF--FYAISVLVQIVLKLTLKKSYFVTVHLLFQVLP-------FFFYTYICY 563
            ...:.|:|..:|.:.  .:|..:|...:..:.|.|...:...|:...:|       |...|....
plant   544 YYKLGSTYLALVWLVPPAFAYGLLEATLSPIRLPKPLKLATLLISLAVPILVSSGSFIQLTGTMI 608

  Fly   564 ATLVTFVPMEGRDGPESSPDIMISVFI---IATAINYA-GFVIPIMHKFRKPKIIFSSFGVITII 624
            ..|:.|     ...|..:|:.:.|..|   |||.|:.: .:::..:|.....|.|.::..:||.:
plant   609 GMLIRF-----DSNPGVTPEWLGSALIAVAIATFISLSMVYLLAYIHLSGAKKSIVTALCIITAL 668

  Fly   625 FIILACTSAGFPFVKQLAPQRYYVLHTQRTFHNLDGTSKQDSGYYIQPVDTRLHELDDTTFKNAE 689
            .:.|..:.....|.:..|       ......|.:| ||.||...:|.........|      |.|
plant   669 SLALVSSGVLPAFTEDTA-------RAVNVVHVVD-TSGQDQVAFISLFSNTPGNL------NME 719

  Fly   690 PESWTAA-TCAAEPYCGLPLYSGRW--IEWKDS-ARWIYSSPPVIPMNINLTQLSKQSLDGNKVR 750
            .|..... .|..|.......:..::  :..||: ..|.....||:.: ||    .|:...|..:.
plant   720 AEQIKEGFRCGRENKIDFVSFEAKYNCVTKKDAEVGWDKHDIPVLRV-IN----DKEREGGRVIA 779

  Fly   751 YEYNLRASDRVMMYIDPLDNVKVTDWSFDHTPLVEKHTPPYLIY--AIYSQTEE----------- 802
            ...:...|.|..:.|| :|.::      |.|..|.:.....|:.  ...|..||
plant   780 VSMDTGGSSRWTLRID-MDEIE------DFTMQVGEEEEEELMIERGEKSSNEEGWHQIQFAGGK 837

  Fly   803 --PLNFWVELEHEEGNTDG-----PYMKL---------VVSEHFQYHPEYYTEEYKE-------F 844
              |.:|.::|..||..:|.     |.:||         .|....:..|.:.|...|.       |
plant   838 KAPTSFVLKLYKEEEVSDDKKKQRPLLKLRTDLNRRTPQVQRVLERLPPFCTMFGKSTSPFTLAF 902

  Fly   845 LATFPDWTYT 854
            ||:.|   ||
plant   903 LASLP---YT 909

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10051	NP_611414.1	M28_Fxna_like	62..369	CDD:193497	102/322 (32%)
CG10051	NP_611414.1	MATE_like	361..>604	CDD:298879	51/279 (18%)
AT5G20660	NP_197566.1	M28_Fxna_like	78..396	CDD:193497	104/333 (31%)
AT5G20660	NP_197566.1	MFS	510..>594	CDD:304372	17/88 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248924at2759
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm3522
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.780