DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10051 and Cpq

DIOPT Version :9

Sequence 1:	NP_611414.1	Gene:	CG10051 / 37222	FlyBaseID:	FBgn0034437	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_061225.2	Gene:	Cpq / 54381	MGIID:	1889205	Length:	470	Species:	Mus musculus

Alignment Length:	320	Identity:	71/320 - (22%)
Similarity:	128/320 - (40%)	Gaps:	45/320 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 SYPKMLYQSEEA-----LHPDKFIGERAMRQLAEYSAIGNKMSGSINNEVHTI-NFLLRE----I 102
            |:.::..::.||     ::...:.|.....|.....|:.....|::.:.:.:: :|.:..    |
Mouse   153 SFDELQRRASEARGKIIVYNQPYTGYEKTVQYRVQGAVEAAKVGAVASLIQSVASFSIYSPHTGI 217

  Fly   103 QKIKD------EARLDLYDIEVDTQYSSG----AFHL--WGMTISYTNLSNVVVKISQKSSDNEN 155
            ||.:|      .|.:.:.|.|:.::.:|.    ..||  ...|...|:..|.|.:|: .|...|.
Mouse   218 QKYQDGVPKIPTACITVEDAEMMSRMASRGNKIVIHLEMGAKTYPDTDSFNTVAEIT-GSMYPEE 281

  Fly   156 YLLVNSHYDSEVQTPAAGDDGVMVVVMLETLRVIS----RSERTLTHPVVFLFNGAEEACMLGSH 216
            .:||:.|.||......|.|||....:..|.|.::.    |.:|||.   :.|:. |||...:|:.
Mouse   282 VVLVSGHLDSWDVGQGALDDGGGAFISWEALSLVKDLGLRPKRTLR---LVLWT-AEEQGGIGAS 342

  Fly   217 GFITQHKWSKNCKALVNLDSTGAGGREVLFQTGPNHPWLAKYYQASVPHPYAQTLAEELFQHNFI 281
            .:...||.:.:..:||....:|......|..||.:.   |:.....|.:........::|. |..
Mouse   343 QYYELHKANISKYSLVMEADSGTFLPTGLQFTGSDK---ARAIMKEVMNLLQPLNVTKVFS-NGE 403

  Fly   282 PSDTDFRIFRDYGGVPGLDMASVMNGYVY--HTEFDNFKNVEYGTYQSTGENVLPLIWAL 339
            .:|.:|.|   ..||||..:...:..|.:  |:..|....::     ....||...:||:
Mouse   404 GTDINFWI---QAGVPGASLRDDLYKYFFFHHSHGDTMTVMD-----PKQMNVAAAVWAV 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10051	NP_611414.1	M28_Fxna_like	62..369	CDD:193497	68/301 (23%)
CG10051	NP_611414.1	MATE_like	361..>604	CDD:298879
Cpq	NP_061225.2	M28_Pgcp_like	45..447	CDD:193504	67/310 (22%)
Cpq	NP_061225.2	PA_M28_2	128..254	CDD:240119	16/100 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900