DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10051 and ermp1

DIOPT Version :9

Sequence 1:	NP_611414.1	Gene:	CG10051 / 37222	FlyBaseID:	FBgn0034437	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	XP_005173917.3	Gene:	ermp1 / 101883637	-ID:	-	Length:	886	Species:	Danio rerio

Alignment Length:	861	Identity:	251/861 - (29%)
Similarity:	420/861 - (48%)	Gaps:	128/861 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PDKFIGERAMRQLAEYSAIGNKMSGSINNEVHTINFLLREIQKIKDEARLDLYDIEVDTQYSSGA 126
            |..|...||.:.|.:.:::|.:..||..||:.|:|:||.:|::|:.|:|...:.|.||.|..:|:
Zfish    84 PGTFNALRARKHLDQITSVGPRTVGSPENEILTVNYLLEQIEQIRSESRSGPHSITVDVQKPTGS 148

  Fly   127 F---HLWGMTISYTNLSNVVVKISQKSSDNENYLLVNSHYDSEVQTPAAGDDGVMVVVMLETLRV 188
            |   .|.|.|..|..::|:.||:..||| .::::|.|.|:||...:|.|.||.|...||||.|..
Zfish   149 FSIDFLGGFTSYYDRVTNIAVKLEPKSS-AQHFMLANCHFDSVANSPGASDDAVSCSVMLEVLHS 212

  Fly   189 ISRSERTLTHPVVFLFNGAEEACMLGSHGFITQHKWSKNCKALVNLDSTGAGGREVLFQTGPNHP 253
            ::.....:.|.|:||||||||..:..||||||||.|::..:|.:||::.|.||:||:|||||.:|
Zfish   213 LANLSTPIKHGVIFLFNGAEENILQASHGFITQHPWAQQVRAFINLEAAGVGGKEVVFQTGPENP 277

  Fly   254 WLAKYYQASVPHPYAQTLAEELFQHNFIPSDTDFRIFRDYGGVPGLDMASVMNGYVYHTEFDNFK 318
            ||.:.|..:..||:|..:.:|:||...|||||||||:||:|.:||:|:|.:.||::|||::|..:
Zfish   278 WLVQAYVRAAVHPFASVVGQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGFIYHTKYDTPE 342

  Fly   319 NVEYGTYQSTGENVLPLIWALANAPELDNTTAYEKGHTVYYDFLGWFMMTYTESVSIAINVVVSV 383
            .:...:.|..|:|:|.::..|..:.||.:::.|..|:.|::|.||..::.|...|:..||.:.:.
Zfish   343 RIHTDSIQRAGDNILSVLQHLVMSDELADSSVYRHGNMVFFDVLGLMVVAYPARVAAIINYLTAA 407

  Fly   384 AAFICIGTSVYIMTLDNGA-------DAPKAVVLRFAIIFLVQAGTLFVACGLTLLVAVFMQGVG 441
            |      |.||:....:|.       |...||.:.....|:.....|.||..||||        |
Zfish   408 A------TLVYLSRKCSGGAGVRYLRDVACAVCVCVLSWFVTLLTLLIVALLLTLL--------G 458

  Fly   442 LAESWY---------YGK----------WMAFGLYF--------CTLFFAFGILPATYIGFTKRK 479
            .:..||         ||.          .:|..||:        ..|||..|:|
Zfish   459 RSMFWYTHFYAAVCLYGSAAAAKIILIHTLAKNLYYTGVSAVDLAELFFDVGLL----------- 512

  Fly   480 TNMKLDQTIACFMHAQCILLALLCIIMTIMGIRSSYFPMVGIFFYAIS-VLVQIVLKLTLKKSYF 543
                    :.|     |.|     :.:|:.|:.|:|.||:.:.|..:| ||::...:.......:
Zfish   513 --------LWC-----CAL-----VFLTLNGLCSAYVPMMMVVFPLLSKVLLRTHFRAKGASLQY 559

  Fly   544 VTVHLLFQVLPFFFYTYICYATLVTFVPMEGRDGPESSPDIMISVFIIATAINYAGFVIPIMHKF 608
            ...:|:...:|:....::.:.....|.|:.||.|.|..||::::..|...|:..:.:::.:::..
Zfish   560 SVFYLMGLSVPYVHIMFLIWVVFEIFTPILGRSGTEIPPDVVLAALITLAAVILSSYLMHLLYLS 624

  Fly   609 RKPKIIFSSFG-VITIIFIILACTSAGFPFVKQLA---PQRYYVLHTQRTFHNLDGT-SKQDSGY 668
            ...|.:.::.| |..::|:::.| ...||:....:   |:|.:|.||.|.||.|||: .:.|||.
Zfish   625 CSTKRMLAALGSVFAVMFVLVGC-GLFFPYSADPSSPRPKRVFVQHTTRVFHALDGSVERSDSGL 688

  Fly   669 YI--------QPVDTRLHELDDTTFKNAEPESWTAATCAAEPYCGLPLYSGRW---IEWKDSARW 722
            :|        |.:...:.:|:|:.....:         ...||||.|     |   :::.....|
Zfish   689 WINSLDYTGMQHISAHVPQLNDSIRTRCQ---------HTLPYCGFP-----WFLPVKFLVKKSW 739

  Fly   723 IYSSP---PVIPMNINLTQLSKQSLDGNKVRYEYNLRASDRVMMYIDPLDNVKVTDWSF-DHTPL 783
            ...:|   |..|:...|  ||:|..:...:|..:..:....:.:|:.|:....:..||| |.||.
Zfish   740 YLPAPAVSPEAPLEFRL--LSRQQSEWGTLRLSFEAKGPTHMSLYLLPVSGASLIGWSFGDGTPR 802

  Fly   784 VEKHTPPYLIYAIYSQTEEPLNFW-VELEHEEGNTDGP----YMKLVVSEHFQYHPEYYTEEYKE 843
            .:.....::.|:  ..|:.|.  | ..||.:.|.:|..    .:.|.:|.|:...|:.::.....
Zfish   803 FDLSGEYFIFYS--HGTDAPA--WRFSLEVQPGVSDASPDEGLLALAISAHYFSGPDKHSPPLHT 863

  Fly   844 FLATFPDWTYTTDWFS 859
            .:.|||||.:.:.|.|
Zfish   864 LINTFPDWAFPSAWSS 879

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10051	NP_611414.1	M28_Fxna_like	62..369	CDD:193497	126/309 (41%)
CG10051	NP_611414.1	MATE_like	361..>604	CDD:298879	60/277 (22%)
ermp1	XP_005173917.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010