DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10051 and naaladl1

DIOPT Version :9

Sequence 1:	NP_611414.1	Gene:	CG10051 / 37222	FlyBaseID:	FBgn0034437	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001091660.1	Gene:	naaladl1 / 100000223	ZFINID:	ZDB-GENE-060526-100	Length:	740	Species:	Danio rerio

Alignment Length:	398	Identity:	83/398 - (20%)
Similarity:	139/398 - (34%)	Gaps:	141/398 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DGGKSRDKKWP--WFGAPI-YAAAAFALFYAAVLPSFYSYPKMLYQ--SEEALH----PDKFIG- 67
            ||..|..:.:|  |:..|. ....::.:.:..:|..:.:..:..|:  .||...    |.:.||
Zfish   227 DGLVSESETYPHSWYLPPSGVERGSYNIDFGDLLTPYLAAKEDTYRRPKEEITGIPPIPTQPIGF 291

  Fly    68 ERAMRQLAE-------------------YSAIGNKMSGSI-NNEVHTINFLLREIQKIKDEARLD 112
            |.|.|.:.|                   ....|.|.:.|. |:.||                 ||
Zfish   292 EDAQRLICELDGEDAPAGWQGAFDCTYKLGGPGFKATSSFTNSTVH-----------------LD 339

  Fly   113 LYDIEVDTQYSSGAFHLWGMTISYTNLSNVVVKISQKSSDNENYLLVNSHYDSEVQ---TPAAGD 174
            .|:||                 ...|.:| |:.:.:.|.:.:.|::..:|.||.|.   .|::|
Zfish   340 TYNIE-----------------KIENSAN-VMGVIRGSVEPDRYVIYGNHRDSWVHGAIDPSSG- 385

  Fly   175 DGVMVVVMLETLRVIS--------RSERTLTHPVVFLFNGAEEACMLGSHGFITQH--KWSKNCK 229
                ..||||..||:.        |..|:    ::|...||||..::||..:..::  |.|:...
Zfish   386 ----TAVMLEITRVLGKMVKEGKWRPRRS----IIFGSWGAEEFGLIGSAEYTEEYFSKLSERTV 442

  Fly   230 ALVNLD-----------STGAGGREVLFQTGPN-----------HPWLAKYYQASVPHPYAQTLA 272
            |.:|:|           |.....:.|||.....           ..|: :||..:.|:
Zfish   443 AYINVDISVFANATLRASASPAAQSVLFTASKQVDAPGTTMSVYDNWI-RYYNRTSPN------- 499

  Fly   273 EELFQHNFIP-------SDTDFRIFRDYGGVPGLDMASVMNGY--------VYHTEFDNFKNVEY 322
                 :..||       :.:|:..|..|.|:..:|::...:..        .|||.:|.|   :|
Zfish   500 -----YGIIPNVGFLTGAGSDYAAFIHYLGITSMDISYYYDQSKTRARIYPAYHTAYDTF---DY 556

  Fly   323 -GTYQSTG 329
             .||...|
Zfish   557 ASTYIDPG 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10051	NP_611414.1	M28_Fxna_like	62..369	CDD:193497	73/340 (21%)
CG10051	NP_611414.1	MATE_like	361..>604	CDD:298879
naaladl1	NP_001091660.1	Zinc_peptidase_like	50..>124	CDD:301362
		PA_GCPII_like	113..338	CDD:239036	23/127 (18%)
		M28_PSMA_like	335..578	CDD:193568	62/290 (21%)
		TFR_dimer	624..736	CDD:282153
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900