Protein Alignment CG11961 and TRE2

DIOPT Version :9

• Sequence 1: NP_001246418.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_014899.1
• Gene: TRE2 / 854430
• SGDID: S000005782
• Length: 809
• Species: Saccharomyces cerevisiae
• Alignment Length: 546
• Identity: 103/546 - (18%)
• Similarity: 177/546 - (32%)
• Gaps: 182/546 - (33%)

  Fly    21 NVDPL-LRPRGSQQYEAQPNGCERAFVQGNKIKWFWAPA---FFGFWLLLYVTISIPACHRLPRP 81
            |:|.: .:|.|..||...         ..:.:.|..:|.   ...||
Yeast   325 NIDVVQSKPVGLPQYSTG---------DASGLNWDGSPVEEKDHKFW------------------ 362

  Fly    82 LTIQDEETH-PDQFIAERAEKNLRELVSLGPRVVGSRQNEMAALKMLSQKMQKIRSGTANDIEVD 145
                 .:|| |...|:.|..|.|...:|.|...|....::            :..||...|:.:|
Yeast   363 -----RQTHIPTIPISTRQGKELLSRLSSGGVTVDDGNSD------------RSNSGKMGDVLID 410

  Fly   146 VQVASGSYVHWSMVNMYQSIQNIVVKISPKNTNSTTYLLVNSHYDSVPAG---PGAGDDGSMVAT 207
            |.:.:.       |.....|.|||.||..:..:....::..|. :|:..|   |..|     .|.
Yeast   411 VDLQTN-------VREKHFIPNIVGKIEGREQSDKAIIIAASR-NSINFGTTYPNFG-----TAA 462

  Fly   208 MMEVLRVLAKSD-----KPLKNPVVFLFNGAEENPLQASHAF---ITQHKWAKYCKALINLDSCG 264
            ::.::::..:..     |||:|.....|.|.|.|...:|...   :|..|...|  :||::...|
Yeast   463 LLSIVQLFQEVKYKFGWKPLRNIYFISFGGTEFNYAGSSELVEQRLTPLKDEIY--SLIDISQLG 525

  Fly   265 --------NGGR--EILFQSGPNHPWLMKNYRR-----------AIKH-----PY------ASTM 297
                    ||..  |:..::   ||.|.|.:.|           .::|     |:      .|.:
Yeast   526 IPFAEKYENGKTRGELSIET---HPLLKKFFNRNAHGNFDISVDNVQHYGDWTPFLANGIPVSVI 587

  Fly   298 GEELFQHNFIPSDT----------------------DFRIFRDHGSVPGLDMAYTYNGFVYHTRH 340
            ..:..::...|::|                      |..::..|.|:..:|
Yeast   588 SSDSTRNRDTPTETSEDKFERVEKILEDEQNQQSVKDLLVYLLHISMELID-------------- 638

  Fly   341 DKAEIFPRGSFQHTGDNLLALVRQIANSPEIENSAKYAKGHTIYFDV--------MGWFLVFYTE 397
            |....|...|:....|..|..:.|.  .||..|.....||...:..:        .||..:.::.
Yeast   639 DPLLHFDIISYVEDIDERLQRLEQA--YPEKLNFTSIIKGLLFWKKIGSEWASWTQGWENIVWSH 701

  Fly   398 TEGVILNVIVSLVSIGICGYAFKLMSVN------SGIKLEKILKKV--GHTLLVQILSVVVGAI- 453
            .:|    :..||:||....:..||.::.      :|:......|.|  |.||:.:..|...|.:
Yeast   702 GDG----IEPSLLSINRWTWNKKLTNIGRRTCSPAGLPNRSFYKNVLFGPTLIQEDKSKNGGNVD 762

  Fly   454 ---LPVLLGLFMDAVHLPLSWFSNSW 476
               .|.:    |||:      :.:.|
Yeast   763 FWTFPGV----MDAI------YDDDW 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	71/376 (19%)
TRE2	NP_014899.1	PA	249..392	CDD:238300	19/98 (19%)
		M28_PMSA_TfR_like	417..643	CDD:349871	46/250 (18%)
		TFR_dimer	668..799	CDD:398094	25/125 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900