DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11961 and Naalad2

DIOPT Version :9

Sequence 1:	NP_001246418.1	Gene:	CG11961 / 37221	FlyBaseID:	FBgn0034436	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001344328.1	Gene:	Naalad2 / 72560	MGIID:	1919810	Length:	778	Species:	Mus musculus

Alignment Length:	393	Identity:	82/393 - (20%)
Similarity:	129/393 - (32%)	Gaps:	125/393 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 RLP--RPLTIQDEETHPDQFIAERAEKNLREL-----------------VSLGPRVVGSRQNEMA 122
            |||  ..:.|.:...||..:  ..||:.||.|                 .::||...||..:
Mouse   308 RLPVEEAVGIPNIPVHPIGY--NDAERLLRNLGGAAPPDKSWKGSLNVSYNIGPGFTGSEYS--- 367

  Fly   123 ALKMLSQKMQKIRSGTANDIEVDVQVASGSYVHWSMVNMYQSIQNIVVKISPKNTNSTTYLLVNS 187
                     :.||                  :|.:.:|....|.|::..|. .:|....|:::..
Mouse   368 ---------RNIR------------------MHVNNINKITRIYNVIGTIR-GSTEPDRYVILGG 404

  Fly   188 HYDSVPAG---PGAGDDGSMVATMMEVLRVLAK----SDKPLKNPVVFLFNGAEENPLQASHAFI 245
            |.||...|   |..|     .|.:.|:.|...|    ..:| :..::|....|||..|..|..:.
Mouse   405 HRDSWVFGGIDPTTG-----TAVLQEIARSFGKLVNGGWRP-RRTIIFASWDAEEFGLLGSTEWA 463

  Fly   246 TQHKWAKYCK----ALINLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEELFQH-- 304
            .::  ||..:    |.||.||...|...:.....|....|:....|.|..|......:.|::.
Mouse   464 EEN--AKLLQERSIAYINSDSAIEGNYTLRVDCTPLLNQLVYKVAREISSPDDGFESKSLYESWL 526

  Fly   305 --------------NFIPSDTDFRIFRDHGSVPGLDMAYT-------YNGF-VYHTRHDKAEIFP 347
                          |.:.|.:||..:.....:......||       |:.: ||||.::..|:.
Mouse   527 EKDPSPENKECPRINKLGSGSDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYETFELV- 590

  Fly   348 RGSFQHTGDNLL-------ALVRQIANSPEIE-NSAKYAK---------------------GHTI 383
            :..:..|....|       |||.::|:|..|. |...|||                     .|.:
Mouse   591 QNFYDPTFKKQLSVAQLRGALVYELADSVVIPFNIQDYAKALKNYAASIFNISKKHDQQLRNHAV 655

  Fly   384 YFD 386
            .||
Mouse   656 SFD 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	77/377 (20%)
Naalad2	NP_001344328.1	Zinc_peptidase_like	86..>142	CDD:326366
		PA_GCPII_like	148..374	CDD:239036	17/97 (18%)
		M28_PSMA_like	376..623	CDD:193568	57/256 (22%)
		TFR_dimer	660..771	CDD:309400
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900