Protein Alignment CG11961 and Tfr2

DIOPT Version :10

• Sequence 1: NP_725876.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_006249178.1
• Gene: Tfr2 / 288562
• RGDID: 1310152
• Length: 838
• Species: Rattus norvegicus
• Alignment Length: 286
• Identity: 61/286 - (21%)
• Similarity: 102/286 - (35%)
• Gaps: 98/286 - (34%)

  Fly   183 LLVNSHYDSVPA--------------------------GPGAGDDGSMVATMMEVLR----VLAK 217
            |:||:|..|.|.                          ||||.......|.::|::|    :::.
  Rat   434 LVVNNHRTSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSS 498

  Fly   218 SDKPLKNPVVFLFNGAEENPLQASHAFITQHKWAK------YCKAL--INLDS--CGNGG----- 267
            ..:|.::.:...::|.:...:.|:       :|.:      :.||:  ::||:  .|:|.
  Rat   499 GFRPRRSLLFISWDGGDFGSVGAT-------EWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKT 556

  Fly   268 --------REILFQ-SGPNHPWLMKNYRRAIKHPYASTMGEELFQHNFIPSDTDFRIFRDHGSVP 323
                    ..||.| ..|||.......:.|..||   :...|:.|.  :|.|:....|.....||
  Rat   557 SPLLVSLIENILKQVDSPNHSGQTLYDQVAFTHP---SWDAEVIQP--LPMDSSAYSFTAFAGVP 616

  Fly   324 GLDMAYTYNGFVY---HTRHDKAEIFP---RGSF--------QHTG--------DNLLAL----- 361
            .::.::..:..||   ||:.|..|...   ||..        |..|        |:||.|
  Rat   617 AVEFSFMEDDRVYPFLHTKEDTYENLHKMLRGRLPAVVLAVAQLAGQLLIRLSHDHLLPLDFGRY 681

  Fly   362 ----VRQIANSPEIENSAKYAKGHTI 383
                :|.|.|..|.....| |:|.|:
  Rat   682 GDVVLRHIGNLNEFSGDLK-ARGLTL 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_725876.1	M28_Fxna_like	91..395	CDD:349872	61/286 (21%)
		MFS	<539..>658	CDD:475125
Tfr2	XP_006249178.1	Zinc_peptidase_like	179..>232	CDD:472712
		PA_TfR	246..436	CDD:239043	1/1 (100%)
		M28_TfR	444..677	CDD:349946	47/244 (19%)
		TFR_dimer	704..828	CDD:461238	1/3 (33%)