Protein Alignment CG11961 and NAALADL2

DIOPT Version :10

• Sequence 1: NP_725876.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_011510914.1
• Gene: NAALADL2 / 254827
• HGNCID: 23219
• Length: 805
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 69/314 - (21%)
• Similarity: 121/314 - (38%)
• Gaps: 73/314 - (23%)

  Fly   116 SRQNEMAAL----------KMLSQKMQKIRSGTANDIEV---DVQVASGSYVHWSMVNMYQSIQN 167
            ||.|..:.|          |::|....:.::...:.:|:   :::|.|   :....|...:::.|
Human   380 SRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVS---MQVQTVTKLKTVTN 441

  Fly   168 IVVKISPKNTNSTTYLLVNSHYDSVPAGPGAGDDGSMVATMMEVLRVLAKSDKPLKNP---VVFL 229
            :|..:... |:...|::|.||:.:..:..|. :..|..|.:...:|.|....|....|   :||.
Human   442 VVGFVMGL-TSPDRYIIVGSHHHTAHSYNGQ-EWASSTAIITAFIRALMSKVKRGWRPDRTIVFC 504

  Fly   230 FNGAEENPLQASHAF--ITQHKWAKYCK--------ALINLDSCGNGGREILFQSGPNHPWLMKN 284
            ..|..        ||  |..::|.:..|        |.|:|.|...|...:...:.|:...|:..
Human   505 SWGGT--------AFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVE 561

  Fly   285 YRRAIKHPYASTMGEELFQHNF----IPSDTDFRIFRDHGSVPGLDMAY----TYNG--FV---- 335
                 |:.:..|...:..:.|.    |..|.|:  |.:|..||.:..||    |..|  |:
Human   562 -----KNNFNCTRRAQCPETNISSIQIQGDADY--FINHLGVPIVQFAYEDIKTLEGPSFLSEAR 619

  Fly   336 YHTRHDK-AEIFPRGSFQHTGDNLLA-LVRQIANSP-----------EIENSAK 376
            :.||..| .|:.|..:...|...|.. ::.||||.|           |::|:.|
Human   620 FSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNNLK 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_725876.1	M28_Fxna_like	91..395	CDD:349872	69/314 (22%)
		MFS	<539..>658	CDD:475125
NAALADL2	XP_011510914.1	PA	268..420	CDD:333703	7/39 (18%)
		M28_PMSA_TfR_like	437..658	CDD:349871	56/237 (24%)
		TFR_dimer	678..791	CDD:461238