Protein Alignment CG11961 and B0495.7

DIOPT Version :9

• Sequence 1: NP_001246418.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_495618.1
• Gene: B0495.7 / 174245
• WormBaseID: WBGene00015206
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 864
• Identity: 268/864 - (31%)
• Similarity: 413/864 - (47%)
• Gaps: 119/864 - (13%)

  Fly    60 FGFWLLLYVTISI-----PACHR-LPRPLTIQDEETHPDQFIAERAEKNLRELVSLGPRVVGSRQ 118
            |..|:...:|::|     .|.|| :|   .::|..:..| |..:||...|::|.:||.|..||..
 Worm    37 FRHWIYFVLTVAIVYAGVVALHRKMP---AVRDGTSFED-FSEQRARVLLKQLTALGSRPSGSDN 97

  Fly   119 NEMAALKMLSQKMQKIRSGT----ANDIEVDVQVASGSY---VHWSMVNMYQSIQNIVVKISPKN 176
            .|:.|..|:..::.||.|..    .|.:|.|||..||.:   ...|....|..|.|:||:|.||.
 Worm    98 LEVKAFGMIQDRIGKIHSVVDEVGVNRLESDVQRPSGCFDLKFLSSFTLCYHKITNVVVRIGPKK 162

  Fly   177 TNSTTYLLVNSHYDSVPAGPGAGDDGSMVATMMEVLRVLAKSDKPLKNPVVFLFNGAEENPLQAS 241
            ..|...||:|.|:|::|..|||.||......||:||.|||.|...|:|.|||||||||||.|||:
 Worm   163 GPSGNSLLLNCHFDTMPDTPGATDDAVACTIMMDVLEVLAHSKTELENDVVFLFNGAEENFLQAA 227

  Fly   242 HAFITQHKWAKYCKALINLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEELFQHNF 306
            |.||.||.|....:|.|||:..|:||||||||:||.:.||::.|.....||:.|.:.:|:||...
 Worm   228 HGFINQHPWRHDIRAFINLEGTGSGGREILFQAGPGNSWLLQTYLENAPHPFCSVLAQEIFQSGI 292

  Fly   307 IPSDTDFRIFRDHGSVPGLDMAYTYNGFVYHTRHDKAEIFPRGSFQHTGDNLLALVRQIANSPEI 371
            ||||||||||||:|.:.|||:|||.||:.|||..|:......|:.|..|:|:||:||.|..||.:
 Worm   293 IPSDTDFRIFRDYGRISGLDIAYTKNGWFYHTEFDEEWRIEPGAIQRAGENVLAVVRAILKSPYL 357

  Fly   372 ENSAKY-AKGHTIYFDVMGWFLVFYTETEGVILNVIV--------------SLVSIGICGYAFKL 421
            |..|.: .:...:::||:|.|.|:|:...|.:||.|.              .|.|:|....|||
 Worm   358 EKPATFDEENRWVFYDVVGLFTVYYSVNVGKLLNYIACFATYFLVVLRIRNRLYSVGDLAIAFK- 421

  Fly   422 MSVNSGIKLEKILKKVGHTLLVQILSVVVGAILPVLLGLFMDAVHLPLSWFSNSWLILGLYFTTF 486
                             |. :|..|::|:..:|.:...:.||.|   :.|:....::..||....
 Worm   422 -----------------HH-VVAFLAMVITMLLIIAFVVQMDLV---MCWYKMPEIVGALYVLPM 465

  Fly   487 FFGLAIVPALYFHWTKRDKLPIGQRVQLLLHCHCLLLSVLTLIFTICGIRSVFVLM----LSCLF 547
            ....|||   :.|:...:::...:.||.    ..:|||..:::|          ||    ||..|
 Worm   466 LIAGAIV---HSHYADNNRIRNVEMVQY----DTILLSFASILF----------LMTFYNLSSAF 513

  Fly   548 YTVGLIINIATKLHTKDVAW----------VIPHIV------CTVPPFVFFAYFSHGFFTTFIPM 596
            |.:.   |:...:....:.|          |.|.::      |.:|.|||.||........|:|:
 Worm   514 YVLN---NLILPVFKDIIIWALGLFGVIRRVTPRVLFFTQLFCFLPTFVFAAYAISQCVDFFVPV 575

  Fly   597 FGRFGENLNPDLAVAVFSVAVGFLCCGFIIPVLQLFNKSKT---IICGLMGI-TLLCFIIAMTPI 657
            .||.|..:||:..:....:.:   ..|||:.|..||..|:.   ||..|..| .|...::..|.:
 Worm   576 MGRLGNAINPEFIMGPLGLVI---ASGFILFVNNLFYISRRMNYIIRLLFAIFALFILVLITTKV 637

  Fly   658 GFPY---RPETNVQRFAVLHTKRTFHDAQNKVRRQESGYFIMPQDRRTYTVKNAVINMTLAQRIG 719
            |.||   .....::|...||..||.:|.:..:.::::..|:...|.|  ...:...:..|.....
 Worm   638 GNPYEYSHENPRLRRIIALHANRTIYDFEGHLTQKDNALFVHSLDYR--GASDLPDHSFLQGSSA 700

  Fly   720 SDCDKEIN--CGLPLYNQRWHK--TRKNSLWIPASEPVLGENVPTVLLLSKNTVSPT-KIRYEMQ 779
            .:|...::  |.:|.|. ..|:  ..:.|||:|...||:......:.|:|::.:... .:.:|::
 Worm   701 PNCTGVVDEYCRMPYYT-AIHELFPPEQSLWVPVPSPVVLPYPIDLKLVSRHAMGENLNLTFEIR 764

  Fly   780 LSGPNHMALFIQPLNGAKMMDWSFHQAPLR-LSFEPPYFIYFSWGVNGDPL-KFWLELEKPNG-- 840
             .|.:.|:|.:.|||...::.|||....:: ......||::.::|.....: :||:.|:..||
 Worm   765 -GGYDKMSLHVTPLNDYDLLSWSFTDIDIKEFGRRQTYFVFMTYGHEAPEVRRFWILLKNKNGVA 828

  Fly   841 --NWNSSTLELGLGGHWNH 857
              ......:||.:..|:.|
 Worm   829 PDPEKHENIELSVATHYAH 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	142/311 (46%)
B0495.7	NP_495618.1	M28_Fxna_like	70..382	CDD:193497	142/312 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158701
Domainoid	1	1.000	230	1.000	Domainoid score	I1390
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	359	1.000	Inparanoid score	I1290
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59376
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		mtm4849
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1738
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840