DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11961 and ermp1

DIOPT Version :9

Sequence 1:	NP_001246418.1	Gene:	CG11961 / 37221	FlyBaseID:	FBgn0034436	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_005173917.3	Gene:	ermp1 / 101883637	-ID:	-	Length:	886	Species:	Danio rerio

Alignment Length:	872	Identity:	263/872 - (30%)
Similarity:	442/872 - (50%)	Gaps:	99/872 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GFWLLLYVTISIPACHRLPRPLTIQDEETHPDQFIAERAEKNLRELVSLGPRVVGSRQNEMAALK 125
            ||..||:..:     |...:.|.|:.    |..|.|.||.|:|.::.|:|||.|||.:||:..:.
Zfish    63 GFVCLLWTLV-----HLSVQQLIIRS----PGTFNALRARKHLDQITSVGPRTVGSPENEILTVN 118

  Fly   126 MLSQKMQKIRSGT---ANDIEVDVQVASGSY---VHWSMVNMYQSIQNIVVKISPKNTNSTTYLL 184
            .|.:::::|||.:   .:.|.||||..:||:   ......:.|..:.||.||:.|| :::..::|
Zfish   119 YLLEQIEQIRSESRSGPHSITVDVQKPTGSFSIDFLGGFTSYYDRVTNIAVKLEPK-SSAQHFML 182

  Fly   185 VNSHYDSVPAGPGAGDDGSMVATMMEVLRVLAKSDKPLKNPVVFLFNGAEENPLQASHAFITQHK 249
            .|.|:|||...|||.||....:.|:|||..||....|:|:.|:|||||||||.|||||.|||||.
Zfish   183 ANCHFDSVANSPGASDDAVSCSVMLEVLHSLANLSTPIKHGVIFLFNGAEENILQASHGFITQHP 247

  Fly   250 WAKYCKALINLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEELFQHNFIPSDTDFR 314
            ||:..:|.|||::.|.||:|::||:||.:|||::.|.||..||:||.:|:|:||...||||||||
Zfish   248 WAQQVRAFINLEAAGVGGKEVVFQTGPENPWLVQAYVRAAVHPFASVVGQEVFQSGIIPSDTDFR 312

  Fly   315 IFRDHGSVPGLDMAYTYNGFVYHTRHDKAEIFPRGSFQHTGDNLLALVRQIANSPEIENSAKYAK 379
            |:||.|::||:|:|:..|||:|||::|..|.....|.|..|||:|::::.:..|.|:.:|:.|..
Zfish   313 IYRDFGNIPGIDLAFIENGFIYHTKYDTPERIHTDSIQRAGDNILSVLQHLVMSDELADSSVYRH 377

  Fly   380 GHTIYFDVMGWFLVFYTETEGVILNVIVSLVSIGICGYAFKLMSVNSGIKLEKILKKVGHTLLVQ 444
            |:.::|||:|..:|.|......|:|.:.:..::   .|..:..|..:|:   :.|:.|...:.|.
Zfish   378 GNMVFFDVLGLMVVAYPARVAAIINYLTAAATL---VYLSRKCSGGAGV---RYLRDVACAVCVC 436

  Fly   445 ILSVVVGAILPVLLGLFMDAVHLPLSWFSNSWLILGLYFTT---------------FFFGLAIV- 493
            :||..|..:..:::.|.:..:...:.|:::.:..:.||.:.               ::.|::.|
Zfish   437 VLSWFVTLLTLLIVALLLTLLGRSMFWYTHFYAAVCLYGSAAAAKIILIHTLAKNLYYTGVSAVD 501

  Fly   494 -PALYFHWTKRDKLPIGQRVQLLLHCHCLLLSVLTLIFTICGIRSVFVLMLSCLFYTVGLIINIA 557
             ..|:|.            |.|||.| |.|     :..|:.|:.|.:|.|:..:|..:..:: :.
Zfish   502 LAELFFD------------VGLLLWC-CAL-----VFLTLNGLCSAYVPMMMVVFPLLSKVL-LR 547

  Fly   558 TKLHTK--DVAWVIPHIVCTVPPFVFFAYFSHGFFTTFIPMFGRFGENLNPDLAVAVFSVAVGFL 620
            |....|  .:.:.:.:::....|:|...:.....|..|.|:.||.|..:.||:.:|........:
Zfish   548 THFRAKGASLQYSVFYLMGLSVPYVHIMFLIWVVFEIFTPILGRSGTEIPPDVVLAALITLAAVI 612

  Fly   621 CCGFIIPVLQLFNKSKTIICGLMGITLLCFIIAMTPIGFPY-------RPETNVQRFAVLHTKRT 678
            ...:::.:|.|...:|.::..|..:..:.|::....:.|||       ||    :|..|.||.|.
Zfish   613 LSSYLMHLLYLSCSTKRMLAALGSVFAVMFVLVGCGLFFPYSADPSSPRP----KRVFVQHTTRV 673

  Fly   679 FHDAQNKVRRQESGYFIMPQDRRTYTVKNAV------INMTLAQRIGSDCDKEI-NCGLPLYNQR 736
            ||.....|.|.:||.:|...|   ||....:      :|.::..|    |...: .||.|
Zfish   674 FHALDGSVERSDSGLWINSLD---YTGMQHISAHVPQLNDSIRTR----CQHTLPYCGFP----- 726

  Fly   737 WHK----TRKNSLWIPASEPVLGENVPTVL-LLSKNTVSPTKIRYEMQLSGPNHMALFIQPLNGA 796
            |..    ..|.|.::||  |.:....|... |||:.......:|...:..||.||:|::.|::||
Zfish   727 WFLPVKFLVKKSWYLPA--PAVSPEAPLEFRLLSRQQSEWGTLRLSFEAKGPTHMSLYLLPVSGA 789

  Fly   797 KMMDWSFHQAPLRLSFEPPYFIYFSWGVNGDPLKFWLELEK--PNGNWNSSTLELGLGGHWNHHK 859
            .::.|||.....|......|||::|.|.:....:|.||::.  .:.:.:...|.|.:..|:....
Zfish   790 SLIGWSFGDGTPRFDLSGEYFIFYSHGTDAPAWRFSLEVQPGVSDASPDEGLLALAISAHYFSGP 854

  Fly   860 ELITPDFKKFLDSFPHYVDATPWPASF 886
            :..:|.....:::||.:...:.|.:::
Zfish   855 DKHSPPLHTLINTFPDWAFPSAWSSTY 881

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	141/309 (46%)
ermp1	XP_005173917.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010