Protein Alignment CG11961 and NAALADL1

DIOPT Version :9

• Sequence 1: NP_001246418.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_005459.2
• Gene: NAALADL1 / 10004
• HGNCID: 23536
• Length: 740
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 82/390 - (21%)
• Similarity: 133/390 - (34%)
• Gaps: 117/390 - (30%)

  Fly    18 DPTNV-DPLLRPRGS--QQYEAQPNGCERAFVQGNKIKWFWAPAFFGFWLLLYVTISIPACHRL- 78
            ||.:: |.|..|..:  ..:...|:|.||    |:..::|..|      |..|:. ::|:..|:
Human   218 DPADINDGLSSPDETFPNSWYLPPSGVER----GSYYEYFGDP------LTPYLP-AVPSSFRVD 271

  Fly    79 --------PRPLTIQDEETHPDQFIAERAEKNLRELV--------------------SLGPRVVG 115
                    |.|       |.|..|      ::.|:|:                    .|||   |
Human   272 LANVSGFPPIP-------TQPIGF------QDARDLLCNLNGTLAPATWQGALGCHYRLGP---G 320

  Fly   116 SRQNEMAALKMLSQKMQKIRSGTANDIEVDVQVASGSYVHWSMVNMYQSIQNIVVKISPKNTNST 180
            .|.:                    .|...|.||....|....:.|....:..|...:.|..
Human   321 FRPD--------------------GDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPDR---- 361

  Fly   181 TYLLVNSHYDSVPAGPGAGDDGSMVATMMEVLRVLA----KSDKPLKNPVVFLFNGAEENPLQAS 241
             |:|..:|.||..  .||.|..|..|.::|:.|||.    |.....:..:||...||||..|..|
Human   362 -YVLYGNHRDSWV--HGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGS 423

  Fly   242 HAFITQ--HKWAKYCKALINLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEELFQ- 303
            ..|..:  :|..:...|.||:|........:..|..|....::.:..:.|:.|....:  .::.
Human   424 TEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGDL--SIYDN 486

  Fly   304 -----------HNFIPS------DTDFRIFRDHGSVPGLDMAYTY-----NGFVYHTRHDKAEIF 346
                       :..:||      .:|:..|.....:..:|:||||     :..:|.|.|...:.|
Human   487 WIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTF 551

  Fly   347  346
            Human   552  551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	63/305 (21%)
NAALADL1	NP_005459.2	Zinc_peptidase_like	46..>121	CDD:387401
		PA_GCPII_like	109..335	CDD:239036	32/163 (20%)
		M28_PSMA_like	<348..587	CDD:349942	48/213 (23%)
		TFR_dimer	616..735	CDD:367885

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900