DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment EndoB and SFC

DIOPT Version :9

Sequence 1:	NP_611410.1	Gene:	EndoB / 37218	FlyBaseID:	FBgn0034433	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_196834.3	Gene:	SFC / 831171	AraportID:	AT5G13300	Length:	827	Species:	Arabidopsis thaliana

Alignment Length:	364	Identity:	76/364 - (20%)
Similarity:	128/364 - (35%)	Gaps:	115/364 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 FEKIEKSK--PKRLSNLEHLALDMIE---------------AGGDFGQDLPYGQALIKVGQAEQK 129
            |.|::.|.  .|:|.::|..|..:.|               .|..:..|:.:..||...|.
plant     3 FTKLDDSPMFRKQLQSMEESAEILRERSLKFYKGCRKYTEGLGEAYDGDIAFASALETFGG---- 63

  Fly   130 LGQCEHDFIATSG---ICFTQPLRKF------LDGEMKTIGKERGILETKRLDLDACKNRVKKAR 185
             |..:...:|..|   ..||..||:.      |..:::.|..:| :|:...:||    :.||:||
plant    64 -GHNDPISVAFGGPVMTKFTIALREIGTYKEVLRSQVEHILNDR-LLQFANMDL----HEVKEAR 122

  Fly   186 SMLGQQS-------------KDGISPE--AVLEQAERDLRVAQAEFDRQAE---ITKL------- 225
            ....:.|             :.|...:  |.|||   :|..:::.|: ||.   :|.|
plant   123 KRFDKASLTYDQAREKFLSLRKGTKSDVAAALEQ---ELHTSRSMFE-QARFNLVTALSNVEAKK 183

  Fly   226 ---LLDGISTSQASHLRHLHAFIQTQVRYYKQCGDVMEQLQRELANLGGPTPYI--PLDVNEASA 285
               .|:.:|.:..:||           ||:||..:::.|::          |||  .|...:.|.
plant   184 RFEFLEAVSGTMDAHL-----------RYFKQGYELLHQME----------PYINQVLTYAQQSR 227

  Fly   286 SKSNISSGAAAR----------------GPGNNHSAN---MAATGHKPNQPMHVSTDQMQRARVL 331
            .:||....|...                ..|:|.|.|   :.|.|...::.:........|.:|.
plant   228 ERSNYEQAALNEKMQEYKRQVDRESRWGSNGSNGSPNGDGIQAIGRSSHKMIDAVMQSAARGKVQ 292

  Fly   332 C---SYDAKDHTELNLSANEVIFVTECSPVNEDYMYGKQ 367
            .   .|.:|..:.|........||.:...:.  |.|.||
plant   293 TIRQGYLSKRSSNLRGDWKRRFFVLDSRGML--YYYRKQ 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EndoB	NP_611410.1	BAR_Endophilin_B	26..266	CDD:153278	51/237 (22%)
EndoB	NP_611410.1	SH3_Endophilin_B	327..378	CDD:212736	11/44 (25%)
SFC	NP_196834.3	BAR_SFC_plant	14..215	CDD:153290	48/235 (20%)
		PH	293..430	CDD:278594	9/39 (23%)
		PH_ACAP	295..434	CDD:270070	9/37 (24%)
		ArfGap	501..639	CDD:279720
		ANK	711..816	CDD:238125
		Ank_4	729..782	CDD:290365
		ANK repeat	729..759	CDD:293786
		ANK repeat	761..792	CDD:293786
		Ank_4	764..816	CDD:290365
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910