Protein Alignment EndoB and sh3glb1

DIOPT Version :10

• Sequence 1: NP_611410.1
• Gene: EndoB / 37218
• FlyBaseID: FBgn0034433
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001016072.1
• Gene: sh3glb1 / 548826
• XenbaseID: XB-GENE-971928
• Length: 361
• Species: Xenopus tropicalis
• Alignment Length: 381
• Identity: 153/381 - (40%)
• Similarity: 242/381 - (63%)
• Gaps: 25/381 - (6%)

  Fly     7 NFNVKNLVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIP 71
            :||||.|..:||:.:||.||.||||.|..|:||.|.|.:||..:|:.||.|||||::.||.:|.|
 Frog     2 DFNVKKLAADAGTFLSRAVQFTEEKFGQAEKTELDAHLENLLSKAECTKVWTEKIMKQTEVLLQP 66

  Fly    72 NPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDFGQDLPYGQALIKVGQAEQKLGQCEHD 136
            ||..|:|:|::||:::..|.||:..|.||..|.:||.:||....||.||||.|:.::::|....:
 Frog    67 NPNARIEEFVYEKLDRKAPSRLNTEEQLAQYMTDAGNEFGPGTAYGNALIKCGETQKRIGVAHRE 131

  Fly   137 FIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSKDGISPEAV 201
            .:.|:.|.|..|||.|::|:.||:.||:.:|:.|||||||.|.|:||||....:.:
 Frog   132 LVQTAAINFLTPLRNFIEGDFKTMSKEKKLLQNKRLDLDAAKTRLKKARVTEARAA--------- 187

  Fly   202 LEQAERDLRVAQAEFDRQAEITKLLLDGISTSQASHLRHLHAFIQTQVRYYKQCGDVMEQLQREL 266
               ||::||:.|:|||||||||:|||:|||::.|.|||.|:.|::.|:.|:.|....|..||::|
 Frog   188 ---AEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYFAQSYQYMLDLQKQL 249

  Fly   267 ANLGGPTPYIPLDVNEAS----ASKSNISSGAAARGPGNNHSANMAATGHKPNQPMHVSTDQMQR 327
            .:.  |:.::. :.|:::    .|.|..|..|:|:.|  :..:::..:|....:    :::..::
 Frog   250 GSF--PSTFVS-NNNQSTLTPMQSVSVPSVSASAQAP--SAKSSLVTSGFTELK----ASNGSRK 305

  Fly   328 ARVLCSYDAKDHTELNLSANEVIFVTECSPVNEDYMYGKQGLLKGLVPRAFVEMLD 383
            ||||..|||.:.:||:|.|:|||.|.....::.|::.|::|..||.||..::|:|:
 Frog   306 ARVLYDYDAANSSELSLLADEVITVYSMPGMDSDWLMGERGHQKGKVPITYLELLN 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoB	NP_611410.1	BAR_Endophilin_B	26..266	CDD:153278	109/239 (46%)
		SH3_Endophilin_B	327..378	CDD:212736	22/50 (44%)
sh3glb1	NP_001016072.1	BAR_Endophilin_B1	21..249	CDD:153300	109/239 (46%)
		SH3_Endophilin_B1	301..361	CDD:212878	23/59 (39%)