Protein Alignment EndoB and Sh3glb1

DIOPT Version :9

• Sequence 1: NP_611410.1
• Gene: EndoB / 37218
• FlyBaseID: FBgn0034433
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001366099.1
• Gene: Sh3glb1 / 54673
• MGIID: 1859730
• Length: 402
• Species: Mus musculus
• Alignment Length: 419
• Identity: 163/419 - (38%)
• Similarity: 245/419 - (58%)
• Gaps: 55/419 - (13%)

  Fly     3 INLPNFNVKNLVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTES 67
            :|:.:||||.|..:||:.:||.||.||||||..|:||.|.|.:||..:|:.||.|||||::.||.
Mouse     1 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEV 65

  Fly    68 VLIPNPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDFGQDLPYGQALIKVGQAEQKLGQ 132
            :|.|||..|:|:|::||:::..|.|::|.|.|...||:||.:||....||.||||.|:.::::|.
Mouse    66 LLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGT 130

  Fly   133 CEHDFIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSK-DGI 196
            .:.:.|.||.:.|..|||.|::|:.|||.|||.:|:.|||||||.|.|:|||::...:.|: :..
Mouse   131 ADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSA 195

  Fly   197 SPEA------------------------VLEQAERDLRVAQAEFDRQAEITKLLLDGISTSQASH 237
            .||.                        .:.::|::||:.|:|||||||||:|||:|||::.|.|
Mouse   196 RPEGDNIMVNFSYMLNFLHVKWLKIWAEEVTKSEQELRITQSEFDRQAEITRLLLEGISSTHAHH 260

  Fly   238 LRHLHAFIQTQVRYYKQCGDVMEQLQRELANL------------GGPTPYIPLDVNEASASKSNI 290
            ||.|:.|::.|:.||.||...|..||::|.:.            |.|.||.   ::.|....:..
Mouse   261 LRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSGTPVPYA---LSNAIGPSAQA 322

  Fly   291 SSGA-AARGPGNNHSANMAATGHKPNQPMHVSTDQMQRARVLCSYDAKDHTELNLSANEVIFVTE 354
            |:|: ....|.|.:....::...|              ||||..|||.:.|||:|.|:|||.|..
Mouse   323 STGSLVITCPSNLNDLKESSNNRK--------------ARVLYDYDAANSTELSLLADEVITVFS 373

  Fly   355 CSPVNEDYMYGKQGLLKGLVPRAFVEMLD 383
            ...::.|::.|::|..||.||..::|:|:
Mouse   374 VVGMDSDWLMGERGNQKGKVPITYLELLN 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoB	NP_611410.1	BAR_Endophilin_B	26..266	CDD:153278	116/264 (44%)
		SH3_Endophilin_B	327..378	CDD:212736	23/50 (46%)
Sh3glb1	NP_001366099.1	BAR_Endophilin_B1	24..289	CDD:153300	116/264 (44%)
		SH3_Endophilin_B1	342..402	CDD:212878	25/73 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	248	1.000	Domainoid score	I2134
eggNOG	1	0.900	-	-		E1_KOG3725
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9337
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2732
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49388
OrthoDB	1	1.010	-	-		D347900at33208
OrthoFinder	1	1.000	-	-		FOG0002653
OrthoInspector	1	1.000	-	-		otm42351
orthoMCL	1	0.900	-	-		OOG6_106332
Panther	1	1.100	-	-	O	PTHR14167
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4112
SonicParanoid	1	1.000	-	-		X1759
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.870