Protein Alignment EndoB and sh3glb2a

DIOPT Version :10

• Sequence 1: NP_611410.1
• Gene: EndoB / 37218
• FlyBaseID: FBgn0034433
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: XP_017212793.1
• Gene: sh3glb2a / 402885
• ZFINID: ZDB-GENE-061201-8
• Length: 386
• Species: Danio rerio
• Alignment Length: 413
• Identity: 171/413 - (41%)
• Similarity: 240/413 - (58%)
• Gaps: 66/413 - (15%)

  Fly     7 NFNVKNLVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIP 71
            :|||:.|..:||...||.||.||||||..|:||.|.||:||..|||.||.|||||.|.||.:|.|
Zfish     2 DFNVRKLASDAGIFFSRAVQFTEEKLGQAEKTELDTHFENLLARADCTKNWTEKIYRQTEVLLQP 66

  Fly    72 NPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDFGQDLPYGQALIKVGQAEQKLGQCEHD 136
            ||..|:|:|::||:::..|.|.:|.|.|:..|:||..:||...|||..|||||..:::||..|.:
Zfish    67 NPGARIEEFLYEKLDRKIPPRATNGEILSQFMLEAAKEFGPGTPYGSTLIKVGDCQRRLGGAERE 131

  Fly   137 FIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSKDGISPE-- 199
            |:..|.|.|..|||.||:|:.:||.:||.:||.:||||||||.|:|||::   .::|....|:
Zfish   132 FLQASSISFLTPLRNFLEGDWRTISRERRLLENRRLDLDACKARLKKAKA---AEAKAAAVPDFQ 193

  Fly   200 ------------------AVLEQAERDLRVAQAEFDRQAEITKLLLDGISTSQASHLRHLHAFIQ 246
                              ..|:::|::|||||||||||||:|:|||:|||::..:|||.|..|.:
Zfish   194 ETRPRNYVLSASASALWSEELDKSEQELRVAQAEFDRQAEVTRLLLEGISSTHVNHLRCLREFAE 258

  Fly   247 TQVRYYKQCGDVMEQLQRELANLGG----PTPYIPLDVN-EASASKSNISSGAAARGPGNNHSAN 306
            .|..||.||...|::|||||.:..|    |.   .|:|| |.|.|.|::.
Zfish   259 AQAMYYNQCHKYMQELQRELGSSSGDIRCPD---SLEVNCEPSGSPSDLL--------------- 305

  Fly   307 MAATGHKPNQPMHVSTDQMQ------------RARVLCSYDAKDHTELNLSANEVIFVTECSPVN 359
                    |.|..:.:|.:|            :||||..|.|.|.:||:|.|:|:|.|.....::
Zfish   306 --------NSPSPLDSDTLQIEEVQPPASGTRKARVLYDYTAADSSELSLRADELITVYTMPGMD 362

  Fly   360 EDYMYGKQGLLKGLVPRAFVEML 382
            .|::.|::|..||.||..::|:|
Zfish   363 SDWLIGERGNQKGKVPVTYLELL 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoB	NP_611410.1	BAR_Endophilin_B	26..266	CDD:153278	124/259 (48%)
		SH3_Endophilin_B	327..378	CDD:212736	21/50 (42%)
sh3glb2a	XP_017212793.1	BAR	21..278	CDD:472257	124/259 (48%)
		SH3	326..386	CDD:473055	23/60 (38%)