Protein Alignment EndoB and Sh3glb2

DIOPT Version :10

• Sequence 1: NP_611410.1
• Gene: EndoB / 37218
• FlyBaseID: FBgn0034433
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: XP_008759883.1
• Gene: Sh3glb2 / 311848
• RGDID: 1305886
• Length: 450
• Species: Rattus norvegicus
• Alignment Length: 453
• Identity: 166/453 - (36%)
• Similarity: 244/453 - (53%)
• Gaps: 82/453 - (18%)

  Fly     7 NFNVKNLVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIP 71
            :||:|.|..:||...:|.||.||||.|..|:||.|.||:||..|||.||.|||:|:|.||.:|.|
  Rat     2 DFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQP 66

  Fly    72 NPQNRVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDFGQDLPYGQALIKVGQAEQKLGQCEHD 136
            ||..|||:|::||:::..|.|::|.|.||..|.||..:.|.:.|||:.|:||.:||::||..|.|
  Rat    67 NPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERD 131

  Fly   137 FIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKAR---------------- 185
            ||.|:.:.|..|||.||:|:.|||.|||.:|:.:||||||||.|:|||:
  Rat   132 FIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETR 196

  Fly   186 -----------SMLGQQSKD----------------------GISPEAVL--------------- 202
                       :.|...|:.                      .::|...|
  Rat   197 PRNYILSASASATLDDTSRSPPWAEWKEKHPGGWRLPCFFLLPLTPSVTLARGCLSLPEDRKLWN 261

  Fly   203 ---EQAERDLRVAQAEFDRQAEITKLLLDGISTSQASHLRHLHAFIQTQVRYYKQCGDVMEQLQR 264
               ::||::||.||.|||||||:|:|||:|||::..:|||.||.|:::|..||.||...|..||:
  Rat   262 DEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQK 326

  Fly   265 ELANLGG---PTPYIPLDVNEASASKSNISSGAAARGPGNNHSANMAATGHKPNQPMHVSTDQM- 325
            :|.:..|   |..::......:....|...:..||..|.....|.:|     |.:...:..:::
  Rat   327 QLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLA-----PPEEAALCLEEVA 386

  Fly   326 ------QRARVLCSYDAKDHTELNLSANEVIFVTECSPVNEDYMYGKQGLLKGLVPRAFVEML 382
                  ::||||..|:|.|.:||.|.|:|:|.|.....::.|::.|::|..||.||..::|:|
  Rat   387 PPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELL 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoB	NP_611410.1	BAR_Endophilin_B	26..266	CDD:153278	125/306 (41%)
		SH3_Endophilin_B	327..378	CDD:212736	21/50 (42%)
Sh3glb2	XP_008759883.1	BAR	21..328	CDD:472257	125/306 (41%)
		SH3_Endophilin_B2	394..448	CDD:212877	21/53 (40%)