Protein Alignment CG7461 and ACOX2

DIOPT Version :9

• Sequence 1: NP_001286611.1
• Gene: CG7461 / 37217
• FlyBaseID: FBgn0034432
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_003491.1
• Gene: ACOX2 / 8309
• HGNCID: 120
• Length: 681
• Species: Homo sapiens
• Alignment Length: 629
• Identity: 130/629 - (20%)
• Similarity: 215/629 - (34%)
• Gaps: 161/629 - (25%)

  Fly    25 HSPKLGAESNRSKEKASENESFM--------ANIFRGSL--------VSSQVFPYPDVLTAEQKE 73
            |...||...:|......|:|.:|        .||..|..        |.|.:..||:....:...
Human     6 HRVSLGDTWSRQMHPDIESERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYPEFSCKDNYF 70

  Fly    74 LTNSLIDPFERFFSDVNDAARNDANSKIDDTTSTALWELGAFGIQ-VPSEFGGLGLNNTQYGRLC 137
            :|.:     ||:    ..|.|.                  ||.|: :....|.|     :.||
Human    71 MTQN-----ERY----KAAMRR------------------AFHIRLIARRLGWL-----EDGR-- 101

  Fly   138 AIVGVNDLGLG-------ITIGAHQSIGFKGILLYGTPEQKEKYLPKVAAEQVYAAFALTEPSSG 195
                  :||..       :.:..|: :..:.:...|:.||..|:.|.....|:.|.:|.||...|
Human   102 ------ELGYAYRALSGDVALNIHR-VFVRALRSLGSEEQIAKWDPLCKNIQIIATYAQTELGHG 159

  Fly   196 SDAGSIRCRAVKSADGKHYV-----LNGSKIWISN-GGIAEIMTVFAQTEQVDPKTGEKKDKVTA 254
            :....:...|...|..:.:|     |..:|.|..: |..|....|.||......:.|     :.|
Human   160 TYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHALVQAQLICSGARRG-----MHA 219

  Fly   255 FIVE-RS------FGGVTNGPPEKKMGIKASNTAEVYFEDVKIPIENVLGKEG----DGFKVAMN 308
            |||. ||      ..|:..|....||....::...:....|::|.||:|.:..    ||..|.:.
Human   220 FIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHVRVPRENMLSRFAQVLPDGTYVKLG 284

  Fly   309 ILNNGRFGM---------GATLSGTMKKCI---EQATEHANNRVQFGQ---KLKNYGSIQEKLAQ 358
            ...:....|         |..|....|.|:   ..:.....:|::...   |:.:|.:.|:||..
Human   285 TAQSNYLPMVVVRVELLSGEILPILQKACVIAMRYSVIRRQSRLRPSDPEAKVLDYQTQQQKLFP 349

  Fly   359 MNILQYATESMA----------FTISQNMD-AGSKDYHLEAAISKIYASESAWYVCDEAIQILGG 412
            ...:.||...:|          :|...|.| :...:.|..:...|...||......:...:..||
Human   350 QLAISYAFHFLAVSLLEFFQHSYTAILNQDFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGG 414

  Fly   413 MGYMVDNGLERVLRDLRIFRIFEGTNDILRLFIALTGIQYAGSHLKELQRAFKNPSANLGLIFKE 477
            .||...:||..::..|.....:||.|.:|.|.:|...::   |:|:........|..:|
Human   415 HGYSKLSGLPSLVTKLSASCTYEGENTVLYLQVARFLVK---SYLQTQMSPGSTPQRSL------ 470

  Fly   478 ASRRAASTVGLGGTDLSGHVVGELLPYAKKTAH--CIDLFGQSVEELLLRYNKNIVNEQILLTRL 540
                :.|...|...||:      ..| |::.|.  |.:|:..:...:.:|..|:.|.
Human   471 ----SPSVAYLTAPDLA------RCP-AQRAADFLCPELYTTAWAHVAVRLIKDSVQ-------- 516

  Fly   541 ANAAIDIYAMVVTQSRSSRAVNLNLPTAQHEL-NMTKALTIQAS 583
                   :...:|||.:.          |||. |.|..:.:||:
Human   517 -------HLQTLTQSGAD----------QHEAWNQTTVIHLQAA 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7461	NP_001286611.1	VLCAD	45..454	CDD:173850	98/475 (21%)
		CaiA	67..446	CDD:224871	89/429 (21%)
ACOX2	NP_003491.1	ACAD	20..655	CDD:324545	126/615 (20%)
		Microbody targeting signal. /evidence=ECO:0000255	679..681

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810