Protein Alignment CG7461 and ACOX1

DIOPT Version :9

• Sequence 1: NP_001286611.1
• Gene: CG7461 / 37217
• FlyBaseID: FBgn0034432
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_004026.2
• Gene: ACOX1 / 51
• HGNCID: 119
• Length: 660
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 134/647 - (20%)
• Similarity: 235/647 - (36%)
• Gaps: 132/647 - (20%)

  Fly    29 LGAESNRSKEKASENESFMANIFRGSLVSSQVFPYPDVLTAEQKELTNSLIDPFERFFSDVNDAA 93
            :..:..|.::.||.|...:.:|..||         |: .|..::|:.|.:::..:....|:|...
Human     1 MNPDLRRERDSASFNPELLTHILDGS---------PE-KTRRRREIENMILNDPDFQHEDLNFLT 55

  Fly    94 RNDANSKIDDTTSTALWELGAFGIQVPSEFGGLGLNNTQYGRLCAIVGVNDLGLGITIGAHQSIG 158
            |:.........::..:.::..|||..|.|.... .|....||...:    ||.||:
Human    56 RSQRYEVAVRKSAIMVKKMREFGIADPDEIMWF-KNFVHRGRPEPL----DLHLGM--------- 106

  Fly   159 FKGILLY-GTPEQKEKYLPKVAAEQVYAAFALTEPSSGSDAGSIRCRAVKSADGKHYVLNGS--- 219
            |...||: .|.||:|::.......::...:|.||...|:....:...|....:.:.::||..
Human   107 FLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVT 171

  Fly   220 --KIWISNGGIAEIMT---VFAQTEQVDPKTGEKKDKVTAFIVE-RSFG------GVTNGPPEKK 272
              |.|  .||:.:...   |.||.     .|..|...:.||||. |..|      |:|.|....|
Human   172 SIKWW--PGGLGKTSNHAIVLAQL-----ITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPK 229

  Fly   273 MGIKASNTAEVYFEDVKIPIENVLGK------EGDGFKVAMNILNNG------RFGMGATLSGTM 325
            .|....:...:..::.:||.||:|.|      :|...|...|.|..|      .|.:|.......
Human   230 FGYDEIDNGYLKMDNHRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALS 294

  Fly   326 KKC---IEQATEHANNRVQFGQ---KLKNYGSIQEKLAQMNILQYATESMA-------FTISQNM 377
            |.|   |..:.....:.::.|:   ::.::.:.|.||..:....||.:.:.       ..|::.:
Human   295 KACTIAIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGI 359

  Fly   378 DAGS----KDYHLEAAISKIYASESAWYVCDEAIQILGGMGYMVDNGLERVLRDLRIFRIFEGTN 438
            ..|.    .:.|...|..|.:.|.:|....:......||.||...:||..:..:......|||.|
Human   360 GQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGEN 424

  Fly   439 DILRLFIAL----------TGIQYAG--SHLKELQRAFKNP----------SANLGLIFKEASR- 480
            .::.|..|.          :|....|  |:|.:|......|          ..|......||.:
Human   425 TVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKL 489

  Fly   481 RAASTVGLGGTDLSGHVVG-------------ELLPYAKKTAHC----IDLFGQSVEELLLRYNK 528
            |||..|.:...:|...|:.             :|:..::  |||    :.||.:.:.::..:..:
Human   490 RAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASE--AHCHYVVVKLFSEKLLKIQDKAIQ 552

  Fly   529 NIVNEQILLTRL----ANAAIDIYAMVVTQSRSSRAVNLNLPTAQHELNMTKALTIQASDRV 586
            .::....||..|    .||...:...::|:.:          ..|....:.:.||:..||.|
Human   553 AVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQ----------ITQVNQRVKELLTLIRSDAV 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7461	NP_001286611.1	VLCAD	45..454	CDD:173850	98/463 (21%)
		CaiA	67..446	CDD:224871	92/423 (22%)
ACOX1	NP_004026.2	AXO	3..637	CDD:173839	134/645 (21%)
		PLN02443	5..651	CDD:178062	134/643 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810