DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7461 and Acoxl

DIOPT Version :9

Sequence 1:	NP_001286611.1	Gene:	CG7461 / 37217	FlyBaseID:	FBgn0034432	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	XP_017447070.1	Gene:	Acoxl / 296138	RGDID:	1306814	Length:	656	Species:	Rattus norvegicus

Alignment Length:	608	Identity:	138/608 - (22%)
Similarity:	220/608 - (36%)	Gaps:	169/608 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 MANIFRGSLVSSQVF-PYPDVLTAEQKELTNSLID-----P-FERFFSDVNDAARNDANSKIDDT 104
            :.|..|.:|.||.:| |..|:...|.::|||..:.     | .:|...| .:..||:..|:
  Rat    26 LKNELRRALESSPLFQPRYDLSLDEMRDLTNQRVKFVLSLPLLKRVLQD-QEEKRNNFISQ---- 85

  Fly   105 TSTALWELGAFGIQVPSEFGGLGLNNTQYGRLCAIVGVNDLGLGITIGAHQSIGFKGILLYGTPE 169
             |..|.|:                       ||.:    |:.:.|..|....:....:...|:||
  Rat    86 -SFVLGEV-----------------------LCMV----DVSMSIKCGVIFLLFGGAVNNLGSPE 122

  Fly   170 QKEKYLPKVAAEQVYAAFALTEPSSGSDAGSIRCRAVKSADGKHYVL-----NGSKIWISNGGIA 229
            ...|:...:..::....||:||...||:...|:..|....|.:.:|:     |..|::|.|....
  Rat   123 HVIKWFRPLKEQKYTGMFAMTEKGHGSNIRGIQTEATFDCDSQEFVIDMPCENAQKMYIGNAMHG 187

  Fly   230 EIMTVFAQTEQVDPKTGEKKDKVTAFIVE------RSFGGVTNGPPEKKMGIKASNTAEVYFEDV 288
            ....||||........|..     .|||.      ..:.|||......|.|:...:...:.|:.|
  Rat   188 NYAAVFAQLIIEGKSQGPH-----CFIVPIRDENGNLYPGVTAIDMMYKEGLNGVDNGILIFDKV 247

  Fly   289 KIPIENVLGKEG----DG------------FKVAMNILNNGRFGMGATLSGTMKKCIEQATEHAN 337
            :||.||:|.|.|    ||            |...:.||...|..:.....|.||..:..|..:::
  Rat   248 RIPRENMLDKLGSVTPDGQYHSPIQSKSARFNAMLAILTPSRLAVTFQAMGAMKLGLMIAIRYSH 312

  Fly   338 NRVQFGQKLKNYGSIQEKLAQMNILQYATESMAFTISQNMDAGSKDYHLEAAISKIYASESAWYV 402
            :|.|||.|.|....|.|.  ||..|:..:                  ||..|::..:.|..|.::
  Rat   313 SRRQFGPKGKEEVKIIEH--QMQALRLMS------------------HLATALALTFTSRHAGHI 357

  Fly   403 CDEAI-----------------------------------QILGGMGYMVDNGLERVLRDLRIFR 432
            .||.|                                   :..||||||::|.|..:..|..:|.
  Rat   358 LDEDILQGRELINRRSLQALMAGLKAYSTWETVRCLQDCRECTGGMGYMMENRLSGLKCDTDVFV 422

  Fly   433 IFEGTNDILRLFIALTGI-QYAGSHLKELQRAFKNPSANLGLI---FKEASRRAASTVGLGGTDL 493
            .|||.|.::...:|...: ||:..|.       |||.  ||:|   .:.|..:..::..:..||.
  Rat   423 TFEGDNVVMLQVVARELLAQYSKQHK-------KNPF--LGMIQNWTETAMDKLRTSFLVFNTDT 478

  Fly   494 SGHVVGELLPYAKKTAHCIDLFGQSV--EELLLRYNKNIVNEQ----------------ILLTRL 540
            .||     |.:..|..:    |.:.|  ..|:.|....:|.|:                :.|..:
  Rat   479 VGH-----LAFLLKAVN----FRERVLQRSLVSRIYYKVVTEKGDFFRAWNSCMHHVISLSLAHV 534

  Fly   541 ANAAIDIYAMVVTQ--SRSSRAV 561
            ...|::.:.:.|.|  :|..:|:
  Rat   535 HRVALEQFTLAVRQCPNREDQAL 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7461	NP_001286611.1	VLCAD	45..454	CDD:173850	112/476 (24%)
CG7461	NP_001286611.1	CaiA	67..446	CDD:224871	101/446 (23%)
Acoxl	XP_017447070.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810