DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7461 and Acad9

DIOPT Version :9

Sequence 1:	NP_001286611.1	Gene:	CG7461 / 37217	FlyBaseID:	FBgn0034432	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_861433.2	Gene:	Acad9 / 294973	RGDID:	727973	Length:	625	Species:	Rattus norvegicus

Alignment Length:	623	Identity:	283/623 - (45%)
Similarity:	386/623 - (61%)	Gaps:	25/623 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AGNASLCRQIATHSPKLGAESNRSKEKASENESFMANIFRGSLVSSQVFPYPDVLTAEQKELTNS 77
            |..||...::.|       |..|:...:.::.||...:|.|.:....|||:|:|...|..|: |.
  Rat    17 AARASRVLRVFT-------ERRRTLHTSLQSCSFAKELFLGHIQQKGVFPFPEVSQEELSEI-NQ 73

  Fly    78 LIDPFERFFSDVNDAARNDANSKIDDTTSTALWELGAFGIQVPSEFGGLGLNNTQYGRLCAIVGV 142
            .:.|.|:||::..|:.:.|...||...|...|..||.||||||.|:|||||:||.|.||..|:.:
  Rat    74 FVGPLEKFFNEEVDSRKIDQEGKIPADTLAKLKSLGLFGIQVPEEYGGLGLSNTMYARLGEIISM 138

  Fly   143 NDLGLGITIGAHQSIGFKGILLYGTPEQKEKYLPKVAAEQVYAAFALTEPSSGSDAGSIRCRAVK 207
             |..:.:|:.|||:||.|||:|.|..|||.|||||:::.:..|||.||||:|||||.||:.||..
  Rat   139 -DASITVTLAAHQAIGLKGIILVGNEEQKAKYLPKLSSGEHIAAFCLTEPASGSDAASIQTRATL 202

  Fly   208 SADGKHYVLNGSKIWISNGGIAEIMTVFAQTEQVDPKTGEKKDKVTAFIVERSFGGVTNGPPEKK 272
            |.|.|::||||||:||:|||:|.|.||||:||.|| ..|..|||:|||||||.|||:|||.||.|
  Rat   203 SEDKKYFVLNGSKVWITNGGLANIFTVFAKTEVVD-SDGSIKDKMTAFIVERDFGGITNGKPEDK 266

  Fly   273 MGIKASNTAEVYFEDVKIPIENVLGKEGDGFKVAMNILNNGRFGMGATLSGTMKKCIEQATEHAN 337
            :||:.|||.||:||:.::|:|||||:.|.||||||||||:|||.||:.::|.:||.|||..|:|.
  Rat   267 LGIRGSNTCEVHFENTRVPVENVLGEVGGGFKVAMNILNSGRFSMGSAVAGMLKKLIEQTAEYAC 331

  Fly   338 NRVQFGQKLKNYGSIQEKLAQMNILQYATESMAFTISQNMD-AGSKDYHLEAAISKIYASESAWY 401
            .|.||.:.|..:|.||||.|.|....|..||||:..|..:| .|..|..:|||:.|:::||:||.
  Rat   332 TRKQFNRNLSEFGLIQEKFALMAQKAYVMESMAYLTSGMLDQPGFPDCSIEAAMVKVFSSEAAWQ 396

  Fly   402 VCDEAIQILGGMGYMVDNGLERVLRDLRIFRIFEGTNDILRLFIALTGIQYAG----SHLKELQR 462
            ...||:|||||.|||.|...||:|||.||..||||||:||||||||||:|:||    |.:|||:
  Rat   397 CVSEALQILGGSGYMKDYPYERMLRDARILLIFEGTNEILRLFIALTGLQHAGRILTSRIKELK- 460

  Fly   463 AFKNPSANLGLIFKEASRR----AASTVGLGGTDLSGHVVGELLPYAKKTAHCIDLFGQSVEELL 523
                 |.|:..:.:...|:    ...||.||.:.....|...|...|.|....:..||::||.||
  Rat   461 -----SGNVTTVMETIGRKLRDSLGRTVDLGLSSNIAVVHPSLGDSANKLEENVHYFGRTVETLL 520

  Fly   524 LRYNKNIVNEQILLTRLANAAIDIYAMVVTQSRSSRAVNLNLPTAQHELNMTKALTIQASDRVIK 588
            ||:.|.||.||::|.|:||..|::|.|....||:||::.:.|....||:.:.....::|..:.:.
  Rat   521 LRFGKTIVEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLKNHDHEILLANMFCVEAYFQNLF 585

  Fly   589 NLQAATSSHHRSLNEKISTIAKTTLENGGVTTTGILDQ 626
            :|.........:|:|:|..:::..||.........||:
  Rat   586 SLSQLDKYAPENLDEQIKKVSQQILEKRAYICAHPLDR 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7461	NP_001286611.1	VLCAD	45..454	CDD:173850	224/409 (55%)
CG7461	NP_001286611.1	CaiA	67..446	CDD:224871	209/379 (55%)
Acad9	NP_861433.2	VLCAD	42..449	CDD:173850	224/409 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56772
OrthoDB	1	1.010	-	-		D163462at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103362
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X967
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830