Protein Alignment CG7461 and acdh-12

DIOPT Version :9

• Sequence 1: NP_001286611.1
• Gene: CG7461 / 37217
• FlyBaseID: FBgn0034432
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_001022062.1
• Gene: acdh-12 / 174180
• WormBaseID: WBGene00017125
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 313/621 - (50%)
• Similarity: 409/621 - (65%)
• Gaps: 32/621 - (5%)

  Fly     6 IQSTRYLAGNASLCRQIATHSPKLGAESNRSKEKASENESFMANIFRGSLVSSQVFPYPDVLTAE 70
            :..||::.         .:||.....::...|..|.::.||:.|:|||..|:.||||||..:|.|
 Worm    11 LNQTRFIR---------LSHSAAAAKDAKPKKVAAVDSPSFVMNLFRGKAVTDQVFPYPLNMTDE 66

  Fly    71 QKELTNSLIDPFERFFSDVNDAARNDANSKIDDTTSTALWELGAFGIQVPSEFGGLGLNNTQYGR 135
            |||....::.|.|:...:|||..:||..|.|.........|||.||:.||.|..|.|.||:|..|
 Worm    67 QKETLGMVMSPLEKMLVEVNDVVKNDETSDIPRAVLDQFAELGTFGVLVPPELEGSGFNNSQMAR 131

  Fly   136 LCAIVGVNDLGLGITIGAHQSIGFKGILLYGTPEQKEKYLPKVAAEQVYAAFALTEPSSGSDAGS 200
            :..|||..|||.|:.:|||||||:|||||.||..||:||||.:|..:.:||||||||::||||.|
 Worm   132 VAEIVGAYDLGFGVVMGAHQSIGYKGILLEGTDAQKQKYLPDLATGRKFAAFALTEPTTGSDASS 196

  Fly   201 IRCRAVKSADGKHYVLNGSKIWISNGGIAEIMTVFAQT--EQVDPKTGEKKDKVTAFIVERSFGG 263
            :|.||..|||||||||||.||||||||.|::.||||||  :|.|   |..|||::||||||:|||
 Worm   197 VRTRAELSADGKHYVLNGGKIWISNGGFADVFTVFAQTPVKQAD---GSTKDKMSAFIVERAFGG 258

  Fly   264 VTNGPPEKKMGIKASNTAEVYFEDVKIPIENVLGKEGDGFKVAMNILNNGRFGMGATLSGTMKKC 328
            ||:||.|||||||.|||.||:|:::|||:||:|||||:|||||||||||||||:.|..:|.||.|
 Worm   259 VTSGPQEKKMGIKGSNTTEVHFDNLKIPVENLLGKEGEGFKVAMNILNNGRFGIPAACTGAMKHC 323

  Fly   329 IEQATEHANNRVQFGQKLKNYGSIQEKLAQMNILQYATESMAFTISQNMDAGSKDYHLEAAISKI 393
            |::..:|...|||||:||:.:|:|||||.:|....|||||:.:.:|.|||.|.|:|.|||||.|:
 Worm   324 IQKTVDHITTRVQFGKKLQEFGNIQEKLVEMISKLYATESIVYMLSSNMDRGIKEYQLEAAIGKV 388

  Fly   394 YASESAWYVCDEAIQILGGMGYMVDNGLERVLRDLRIFRIFEGTNDILRLFIALTGIQYAGSHLK 458
            .|||:||.|||:|||:.||||:|.:.|||||||||||||||||.||:|||||||||.|:||.||.
 Worm   389 LASENAWLVCDDAIQVHGGMGFMRETGLERVLRDLRIFRIFEGANDVLRLFIALTGAQHAGKHLA 453

  Fly   459 ELQRAFKNPSANLGLIFKEASRRAASTVGLGGTDLSGHVVGELLPYAKKTAHCIDLFGQSVEELL 523
            |      ..|...|||....||   .|.|..|::....|...|...||.....|.||||:|:.||
 Worm   454 E------QASGVGGLIGLAVSR---VTGGNTGSNFGQVVDASLQDSAKVLDQQIALFGQTVQGLL 509

  Fly   524 LRYNKNIVNEQILLTRLANAAIDIYAMVVTQSRSSRAVNLNLPTAQHELNMT-----KALTIQAS 583
            :::.|.|::.|..:.|:|:|||:||:.....||::.|:.....:|..|..:.     ||:  ::|
 Worm   510 MKHKKGIIDRQYEMHRVADAAINIYSSAAVLSRATYAIKNKSSSADFERKVATYYVDKAM--KSS 572

  Fly   584 DRVIKNLQAATSSHHRSLNEKISTIAKTTLENGGVT 619
            :|.:|:  |.:...:.|....|.::||....|||:|
 Worm   573 NRFLKD--AGSGVENASKVATIESLAKEVCGNGGLT 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7461	NP_001286611.1	VLCAD	45..454	CDD:173850	252/410 (61%)
		CaiA	67..446	CDD:224871	233/380 (61%)
acdh-12	NP_001022062.1	VLCAD	41..449	CDD:173850	252/410 (61%)
		CaiA	61..441	CDD:224871	233/382 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157724
Domainoid	1	1.000	201	1.000	Domainoid score	I1755
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5
Inparanoid	1	1.050	569	1.000	Inparanoid score	I578
Isobase	1	0.950	-	0.946395	Normalized mean entropy	S2974
OMA	1	1.010	-	-		QHG56772
OrthoDB	1	1.010	-	-		D163462at33208
OrthoFinder	1	1.000	-	-		FOG0005246
OrthoInspector	1	1.000	-	-		oto19241
orthoMCL	1	0.900	-	-		OOG6_103362
Panther	1	1.100	-	-	LDO	PTHR43884
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X967
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.860