Protein Alignment Tab2 and tab3

DIOPT Version :9

• Sequence 1: NP_001246417.1
• Gene: Tab2 / 37216
• FlyBaseID: FBgn0086358
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001038570.1
• Gene: tab3 / 566547
• ZFINID: ZDB-GENE-060503-408
• Length: 573
• Species: Danio rerio
• Alignment Length: 810
• Identity: 143/810 - (17%)
• Similarity: 226/810 - (27%)
• Gaps: 371/810 - (45%)

  Fly   101 LFHEMKQEFPTIPDAIVTQCVNENCHQRENCIQMLRKELALHPIPVQSYPAKVLQQQQQQHHQNR 165
            :..:::|.||.||:.:|:|.:.:|.:..:.|..:|.:|...:.......|..:        |.||
Zfish    13 ILQDLRQRFPEIPETVVSQYLLQNNNNADLCYHLLAQESNRYLYEEYHSPDDL--------HLNR 69

  Fly   166 QAKPPTPLKPSRIAPPQPEAVLSNGVATPPGVGSPHPDTQ---PRPRPTTLNLQRQFSTQLQQKI 227
            ...    |:.| :..|.|:.|.:|    |.|....|..:.   ..||       ..||..|.
Zfish    70 NHM----LRIS-VGYPVPDGVKNN----PGGRALVHSSSDGHIEHPR-------SGFSEPLS--- 115

  Fly   228 MQRQQRQQRDHQPAQLTPTSLSKPL------RRAPPLPPPPKPKPGSFSNDSSCLTSPMSSSESE 286
                       .||.:.|:....|.      |...|.|||
Zfish   116 -----------APATMAPSPGYNPFFKTDQSRSNIPTPPP------------------------- 144

  Fly   287 LSLNAVPLSSPTSAAATAAAASAAIASTQQQPSPVRHRSVITLQPEPPYARDFRSIDFPPTTACT 351
                ::|..|||....:.......:..:|..||          .|:        ::..||.|.||
Zfish   145 ----SIPGMSPTYHPVSRYMTPITVTLSQNMPS----------APQ--------ALQIPPGTYCT 187

  Fly   352 P-----RLPSPSSAASP----------------SAPGGRKSFTSLNLTLRQPTGSAQSAIDITAG 395
            .     ..||||.:..|                :.|..:..::|....::||   .|..:.|:..
Zfish   188 SGNTVYMRPSPSQSPQPTPWSTSGTSMYQQSPYATPTYQSPYSSPQHQVQQP---PQVFLPISPP 249

  Fly   396 PAPSGQGSGITY-----SSVSFDARRGTQKNFQLTVTDEGSVFSAGSVRPRTLYATPCEPVTSVP 455
            ..|     |::|     |...|.:.:|..|| |:.:|.||.       |||
Zfish   250 TLP-----GLSYQQTPVSQRPFISSKGPMKN-QIEITLEGQ-------RPR-------------- 287

  Fly   456 ANQQPPPPAAVVADGLGDADMTSDVFPYPTQEQNHIVASNYSNNHAVSDNNNIGISNSTDSSPTM 520
                                                                   |||...:|..
Zfish   288 -------------------------------------------------------SNSPVHTPQG 297

  Fly   521 PLYEGVMEECDREARAATIERQKQRRDKLANALRDNKKRLLVLEQEINILTEPVPVGESERLDRD 585
            .||                                             :.|.|.|...|..:.
Zfish   298 ALY---------------------------------------------MATSPSPSSPSRAIS-- 315

  Fly   586 IKQLTEDCNRLLDCLNEPQANGPGPAANPTNRQHLLPASNASQQQPQQQPQPF------PRQRQS 644
                              .|..||.:.:.....|...|.......||..|..|      |||.|.
Zfish   316 ------------------MAGPPGASIHQGMYAHQAVARPRPTSSPQPAPSAFIKIKVSPRQVQG 362

  Fly   645 A-------------------RVQAPPSSLRLHSVPAAPISQPVQDFGQHHSS-----APTSACLT 685
            :                   |..|||..|.:.::|.: |:..:....:..||     |.|.|.|.
Zfish   363 SSNSPPVETESLLNIVDQGERHGAPPPILPISALPGS-IANQINCMPRRSSSGSDDYAYTQALLL 426

  Fly   686 PQMQSQQQLLQLQQEPPPTYAQYYQFQQYLQQQRQQQLQQQMQQQQ--QLQHQMQQQQQ----PQ 744
            .|....::|::               :..|::|:..||:.::.:.:  .||.:.::...    |:
Zfish   427 HQRARMERLMK---------------ELMLERQKLDQLKAEVNEMEFDALQRRFRRVNSTSLIPR 476

  Fly   745 PQQEEEFLSDS-----DVD---EEEETLDS----------------------------------- 766
            |::..:..|.:     |:|   :|.:.|.|
Zfish   477 PEEMTKIRSQNRQLQIDIDCTLKETDLLQSRGKFDLRTMNNFYDNIQPGPVVPPRAKPTAVQRDE 541

  Fly   767 ------WACNMCTFRNHPQLNICEACENVR 790
                  |.|..|||.|||.|:.||.||..|
Zfish   542 DFEGAQWNCESCTFLNHPALHRCEQCEMPR 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tab2	NP_001246417.1	CUE_TAB2_TAB3	98..138	CDD:270545	10/36 (28%)
		NYD-SP28	528..>602	CDD:291438	4/73 (5%)
		ZnF_RBZ	765..789	CDD:197784	14/64 (22%)
		RanBP2-type Zn finger	767..786	CDD:275376	11/18 (61%)
tab3	NP_001038570.1	CUE_TAB2_TAB3	10..51	CDD:270545	10/37 (27%)
		ZnF_RBZ	547..570	CDD:197784	13/22 (59%)
		RanBP2-type Zn finger	548..567	CDD:275376	11/18 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8541
eggNOG	1	0.900	-	-		E1_28IZ6
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	85	1.000	Inparanoid score	I5150
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950