DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tab2 and Tnfrsf1a

DIOPT Version :9

Sequence 1:NP_001246417.1 Gene:Tab2 / 37216 FlyBaseID:FBgn0086358 Length:831 Species:Drosophila melanogaster
Sequence 2:NP_035739.2 Gene:Tnfrsf1a / 21937 MGIID:1314884 Length:454 Species:Mus musculus


Alignment Length:246 Identity:60/246 - (24%)
Similarity:90/246 - (36%) Gaps:50/246 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   371 SFTSLNLTLRQPTGSAQSAIDITAGPAPSGQ---GSGITYS-SVSFDARRGTQKNFQLTVTDEGS 431
            ||..::|..|.|....:....|...|.|..:   |..:|.: |.:|....|    |..|:.....
Mouse   227 SFIFISLMCRYPRWRPEVYSIICRDPVPVKEEKAGKPLTPAPSPAFSPTSG----FNPTLGFSTP 287

  Fly   432 VFSAGSVRPRTLYATPCEPVTSVPANQQPPPPAAVV-----ADGLGDADMTSDVFPYPTQEQNHI 491
            .||:      .:.:||..|:.. |:|....||.:.|     ||.|....:.|  .|.||..|.. 
Mouse   288 GFSS------PVSSTPISPIFG-PSNWHFMPPVSEVVPTQGADPLLYESLCS--VPAPTSVQKW- 342

  Fly   492 VASNYSNNHAVSDNNNIGISNS-TDSSPT---------MPLYEGVME-------ECDREARAATI 539
               ..|.:....||.::.|..: .|..|.         |.|.|..:|       .|.|||:.:.:
Mouse   343 ---EDSAHPQRPDNADLAILYAVVDGVPPARWKEFMRFMGLSEHEIERLEMQNGRCLREAQYSML 404

  Fly   540 ERQKQRRDKLANALRD-----NKKRLL-VLEQEINILTEPVPVGESERLDR 584
            |..::|..:..:.|..     :|..|. .||..:..|..|.| ..:.||.|
Mouse   405 EAWRRRTPRHEDTLEVVGLVLSKMNLAGCLENILEALRNPAP-SSTTRLPR 454

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tab2NP_001246417.1 CUE_TAB2_TAB3 98..138 CDD:270545
NYD-SP28 528..>602 CDD:291438 18/70 (26%)
ZnF_RBZ 765..789 CDD:197784
RanBP2-type Zn finger 767..786 CDD:275376
Tnfrsf1aNP_035739.2 TNFR-Cys 1 43..82
TNFRSF1A 44..175 CDD:276902
CRD1 44..81 CDD:276902
TNFR-Cys 2 83..125
CRD2 84..125 CDD:276902
TNFR-Cys 3 126..166
CRD3 127..166 CDD:276902
TNFR-Cys 4 167..196
N-SMase activation domain (NSD) 339..349 2/13 (15%)
Death_TNFR1 358..437 CDD:176729 18/78 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S8052
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.950

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