Protein Alignment Tab2 and tab2

DIOPT Version :9

• Sequence 1: NP_001246417.1
• Gene: Tab2 / 37216
• FlyBaseID: FBgn0086358
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001090763.1
• Gene: tab2 / 100037849
• XenbaseID: XB-GENE-975095
• Length: 690
• Species: Xenopus tropicalis
• Alignment Length: 871
• Identity: 173/871 - (19%)
• Similarity: 262/871 - (30%)
• Gaps: 375/871 - (43%)

  Fly   101 LFHEMKQEFPTIPDAIVTQCVNENCHQRENCIQMLRK----------ELALHPIP----VQSYPA 151
            :.|.::|:||.:|:.:|::|:.:|.:..:.|..:|.:          ||:|...|    ::::..
 Frog    12 VLHNLRQKFPEVPEVVVSRCMQQNNNNLDACCAVLSQESTKYLYGEGELSLSDDPRIASLRNHMT 76

  Fly   152 KVLQQQQQQH---------HQNRQAKPPT-PLKPSRIAPPQPEAVLSNGVATPPGVGSPHPDTQP 206
            .:....|.|:         ..|..::..| .:....:          :||.:...:..|.|.|.|
 Frog    77 SLNLDLQSQNVYLDGRDGTRMNGNSRTLTHSISDGHL----------HGVQSSNELYQPEPQTAP 131

  Fly   207 RPRPTTLNL------------QRQFSTQLQQKIMQRQQRQQ---------RDHQPAQLTPTSLSK 250
            ...|.:.|:            ..||...|..|.....|..:         .:.||::.|||||
 Frog   132 AHVPASFNVFGMANTINSSNSGHQFGLHLGSKGSSVSQTPRFNPIMVTLAPNIQPSRNTPTSL-- 194

  Fly   251 PLRRAPPLPPPPKPKPGSFSNDSSCLTSPMSSSESELSLNAVPLSSPTSAAATAAAASAAIASTQ 315
               ....:|||             .|.||..:     |:...|.  .||.:.||..|       |
 Frog   195 ---HIHGVPPP-------------ILNSPHGN-----SIYIRPY--VTSQSGTARQA-------Q 229

  Fly   316 QQPSPVRHRSVITLQPE--------------PPYARDFRSIDFP-------------------PT 347
            |.||.|.|...   ||:              |.|:....|:..|                   ||
 Frog   230 QSPSWVSHNPT---QPQQIYQPSQPNPWTTLPTYSAPHTSLQQPTQSSIQGHQTSHVYMPISSPT 291

  Fly   348 TACTPRLPSPSSAASPS--------APGGRKSFTSLNLTLRQPTGSAQSAIDITAGPAPSGQGSG 404
            |...|.|.|..|.:.||        :.|.||:  .:.:.|..|..|..|.:      .||...|.
 Frog   292 TPQAPMLHSSGSGSQPSTQYNIQNISTGPRKN--QIEIKLEPPQRSNSSML------RPSSSRSS 348

  Fly   405 ITYSSVSFDARRGTQKNFQLTV-------TDE------GSVFSAGSVR---------PRTLYATP 447
            ...:|::...|.      |.||       |||      ..|:.:.:.:         |.|::.:.
 Frog   349 ANPASINSQTRN------QPTVYIASPPSTDEMICRNQPKVYISANPQSVDDQVIRNPPTVFISA 407

  Fly   448 CEPVTSVPAN-------------QQPPPPAAVVADGLGDADMTSDVFPYPTQEQNHIVASNYSNN 499
            ....|:.|.|             ..||...|       ..:.||...|.....|.:   :.|:..
 Frog   408 NPGATTAPRNMSGQLSMGPAFIHHHPPKSRA-------HGNSTSATSPRVVVTQPN---TKYTFK 462

  Fly   500 HAVSDNNNIGISNSTDS---SPTMPL--------YEGVMEECD--------REAR---------- 535
            ..||.|....:|....|   .||..|        .||:....|        .|||
 Frog   463 ITVSPNKPPAVSPGVVSPTFEPTNLLNLTDPFAESEGMQHLTDPILASDKISEARKLSVGSDDAA 527

  Fly   536 --AATIERQKQRRDKLANALRDNKKRLLVLEQEINILTEPVPVGESERLDR-----------DIK 587
              .|.:..||.|.::|...|...||:|..|:.|:|.:...:   ...||:|           :::
 Frog   528 YTQALLVHQKARMERLHRELDVQKKKLDQLKTEVNEMENNL---TKRRLNRSNSLSQIPSLEEMQ 589

  Fly   588 QLTEDCNRLL----DCLNEP----QANGPGPAANPTNRQHLLPASNASQQQPQQQPQPFPRQRQS 644
            || ..|||.|    |||.:.    ||.||          |..|::
 Frog   590 QL-RSCNRQLQIDIDCLTKEIDLFQARGP----------HFNPSA-------------------- 623

  Fly   645 ARVQAPPSSLRLHS----------VPAAPISQPVQDFGQHHSSAPTSACLTPQMQSQQQLLQLQQ 699
                       :|:          ||..|..|             .|...||:
 Frog   624 -----------IHNFYDNIGFLGPVPPKPKDQ-------------RSTSKTPK------------ 652

  Fly   700 EPPPTYAQYYQFQQYLQQQRQQQLQQQMQQQQQLQHQMQQQQQPQPQQEEEFLSDSDVDEEEETL 764
                                                                 :.|:::|:|..
 Frog   653 -----------------------------------------------------NTSEMEEDEGA- 663

  Fly   765 DSWACNMCTFRNHPQLNICEACENVR 790
             .|.|..|||.|||.||.||.|:..|
 Frog   664 -HWNCTACTFLNHPALNRCEQCDMPR 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tab2	NP_001246417.1	CUE_TAB2_TAB3	98..138	CDD:270545	10/46 (22%)
		NYD-SP28	528..>602	CDD:291438	28/108 (26%)
		ZnF_RBZ	765..789	CDD:197784	13/23 (57%)
		RanBP2-type Zn finger	767..786	CDD:275376	12/18 (67%)
tab2	NP_001090763.1	CUE_TAB2_TAB3	9..50	CDD:270545	10/37 (27%)
		PHA03247	<164..500	CDD:223021	83/394 (21%)
		SMC_prok_B	<524..>609	CDD:274008	24/88 (27%)
		ZnF_RBZ	664..687	CDD:197784	13/22 (59%)
		RanBP2-type Zn finger	665..684	CDD:275376	12/18 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I5067
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050