Protein Alignment Fkbp12 and FKBP14

DIOPT Version :9

• Sequence 1: NP_523792.2
• Gene: Fkbp12 / 37214
• FlyBaseID: FBgn0013954
• Length: 108
• Species: Drosophila melanogaster
• Sequence 2: NP_060416.1
• Gene: FKBP14 / 55033
• HGNCID: 18625
• Length: 211
• Species: Homo sapiens
• Alignment Length: 93
• Identity: 40/93 - (43%)
• Similarity: 58/93 - (62%)
• Gaps: 4/93 - (4%)

  Fly    18 KNGQKVTVHYTGTLD-DGTKFDSSRDRN--KPFKFTIGKGEVIRGWDEGVAQLSVGQRAKLICSP 79
            |.|..:.|||.|.|: ||:.|.|:...|  :|..||:|..|.::|||:|:..:.||::.|||..|
Human    43 KGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPP 107

  Fly    80 DYAYGSRGHPGVIPPNSTLTFDVELLKV 107
            ...||..| .|.|||.|||.|:::||::
Human   108 ALGYGKEG-KGKIPPESTLIFNIDLLEI 134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp12	NP_523792.2	FkpA	<2..107	CDD:223619	40/91 (44%)
FKBP14	NP_060416.1	FkpA	<43..135	CDD:223619	40/93 (43%)
		EF-hand_7	141..204	CDD:404394
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	208..211

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810