DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fkbp12 and FKBP11

DIOPT Version :9

Sequence 1:NP_523792.2 Gene:Fkbp12 / 37214 FlyBaseID:FBgn0013954 Length:108 Species:Drosophila melanogaster
Sequence 2:NP_057678.1 Gene:FKBP11 / 51303 HGNCID:18624 Length:201 Species:Homo sapiens


Alignment Length:86 Identity:30/86 - (34%)
Similarity:51/86 - (59%) Gaps:1/86 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 GQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQLSVGQRAKLICSPDYAYG 84
            |..:.:||||:|.||...|:|..|: |....:|:.:||.|.::.:..:.||::.:.|.....|||
Human    57 GDTLHIHYTGSLVDGRIIDTSLTRD-PLVIELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYG 120

  Fly    85 SRGHPGVIPPNSTLTFDVELL 105
            .||.|..:|.::.:.:||||:
Human   121 KRGFPPSVPADAVVQYDVELI 141

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp12NP_523792.2 FkpA <2..107 CDD:223619 30/86 (35%)
FKBP11NP_057678.1 FKBP_C 50..141 CDD:365980 29/84 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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