DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fkbp12 and fkbp5

DIOPT Version :9

Sequence 1:NP_523792.2 Gene:Fkbp12 / 37214 FlyBaseID:FBgn0013954 Length:108 Species:Drosophila melanogaster
Sequence 2:XP_005166078.1 Gene:fkbp5 / 368924 ZFINID:ZDB-GENE-030616-630 Length:477 Species:Danio rerio


Alignment Length:89 Identity:48/89 - (53%)
Similarity:61/89 - (68%) Gaps:0/89 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 PKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQLSVGQRAKLICSPDY 81
            |..|.:|.|||||.|..|.|||||.||.:||.|.:|||:||:.||..|..:..|:...::|.|:|
Zfish    71 PMIGDRVFVHYTGRLLSGKKFDSSLDRKEPFVFNVGKGQVIKAWDICVCSMQKGEVCLMLCKPEY 135

  Fly    82 AYGSRGHPGVIPPNSTLTFDVELL 105
            ||||.|.|..:||||||.|::|||
Zfish   136 AYGSAGSPPKVPPNSTLVFEIELL 159

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp12NP_523792.2 FkpA <2..107 CDD:223619 48/89 (54%)
fkbp5XP_005166078.1 FKBP_C 69..159 CDD:278674 46/87 (53%)
FkpA <167..271 CDD:223619
TPR_11 291..372 CDD:290150
TPR repeat 292..320 CDD:276809
TPR repeat 340..370 CDD:276809
TPR_11 343..405 CDD:290150
TPR 343..374 CDD:197478
TPR repeat 375..403 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100299
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.710

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